'Drugs from Bugs': bacterial effector proteins as promising biological (immune-) therapeutics

被引:0
作者
Rueter, Christian [1 ]
Hardwidge, Philip R. [2 ]
机构
[1] Univ Munster, Inst Infectiol, Ctr Mol Biol Inflammat ZMBE, D-48149 Munster, Germany
[2] Kansas State Univ, Coll Vet Med, Manhattan, KS 66506 USA
关键词
NF-KAPPA-B; CELL-PENETRATING PEPTIDE; SIGNALING RESPONSES; YERSINIA; IDENTIFICATION; AUTOIMMUNE; PHOSPHORYLATION; TRANSLOCATION; SECRETION; MECHANISM;
D O I
暂无
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
引用
收藏
页码:126 / 132
页数:7
相关论文
共 52 条
  • [21] Langel u, 2010, HDB CELL PENETRATING, P401
  • [22] The phosphothreonine lyase activity of a bacterial type III effector family
    Li, Hongtao
    Xu, Hao
    Zhou, Yan
    Zhang, Jie
    Long, Chengzu
    Li, Shuqin
    Chen, She
    Zhou, Jian-Min
    Shao, Feng
    [J]. SCIENCE, 2007, 315 (5814) : 1000 - 1003
  • [23] Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains
    Li, Shan
    Zhang, Li
    Yao, Qing
    Li, Lin
    Dong, Na
    Rong, Jie
    Gao, Wenqing
    Ding, Xiaojun
    Sun, Liming
    Chen, Xing
    Chen, She
    Shao, Feng
    [J]. NATURE, 2013, 501 (7466) : 242 - +
  • [24] Translocated effectors of Yersinia
    Matsumoto, Hiroyuki
    Young, Glenn M.
    [J]. CURRENT OPINION IN MICROBIOLOGY, 2009, 12 (01) : 94 - 100
  • [25] Cytokines in the pathogenesis of rheumatoid arthritis
    McInnes, Iain B.
    Schett, Georg
    [J]. NATURE REVIEWS IMMUNOLOGY, 2007, 7 (06) : 429 - 442
  • [26] Delineation of Regions of the Yersinia YopM Protein Required for Interaction with the RSK1 and PRK2 Host Kinases and Their Requirement for Interleukin-10 Production and Virulence
    McPhee, Joseph B.
    Mena, Patricio
    Bliska, James B.
    [J]. INFECTION AND IMMUNITY, 2010, 78 (08) : 3529 - 3539
  • [27] Identification of a synovial fibroblast-specific protein transduction domain for delivery of apoptotic agents to hyperplastic synovium
    Mi, ZB
    Lu, XL
    Mai, JC
    Bobby, GN
    Wang, GQ
    Lechman, ER
    Watkins, SC
    Rabinowich, H
    Robbins, PD
    [J]. MOLECULAR THERAPY, 2003, 8 (02) : 295 - 305
  • [28] Esp-independent functional integration of the translocated intimin receptor (Tir) of enteropathogenic Escherichia coli (EPEC) into host cell membranes
    Michgehl, S
    Heusipp, G
    Greune, L
    Rüter, C
    Schmidt, MA
    [J]. CELLULAR MICROBIOLOGY, 2006, 8 (04) : 625 - 633
  • [29] Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation
    Mukherjee, Sohini
    Keitany, Gladys
    Li, Yan
    Wang, Yong
    Ball, Haydn L.
    Goldsmith, Elizabeth J.
    Orth, Kim
    [J]. SCIENCE, 2006, 312 (5777) : 1211 - 1214
  • [30] The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65
    Newton, Hayley J.
    Pearson, Jaclyn S.
    Badea, Luminita
    Kelly, Michelle
    Lucas, Mark
    Holloway, Gavan
    Wagstaff, Kylie M.
    Dunstone, Michelle A.
    Sloan, Joan
    Whisstock, James C.
    Kaper, James B.
    Robins-Browne, Roy M.
    Jans, David A.
    Frankel, Gad
    Phillips, Alan D.
    Coulson, Barbara S.
    Hartland, Elizabeth L.
    [J]. PLOS PATHOGENS, 2010, 6 (05) : 1 - 16