Long-term follow-up of treatment with imatinib in eosinophilia-associated myeloid/lymphoid neoplasms with PDGFR rearrangements in blast phase

被引:50
作者
Metzgeroth, G. [1 ]
Schwaab, J. [1 ]
Gosenca, D. [1 ]
Fabarius, A. [1 ]
Haferlach, C. [2 ]
Hochhaus, A. [3 ]
Cross, N. C. P. [4 ,5 ]
Hofmann, W-K [1 ]
Reiter, A. [1 ]
机构
[1] Univ Med Mannheim, Med Klin 3, Mannheim, Germany
[2] Munchner Leukamie Lab, Munich, Germany
[3] Univ Klinikum Jena, Klin Innere Med 2, Abt Hamatol Onkol, Jena, Germany
[4] Wessex Reg Genet Lab, Salisbury, Wilts, England
[5] Univ Southampton, Fac Med, Southampton SO9 5NH, Hants, England
关键词
GROWTH-FACTOR RECEPTOR; MYELOPROLIFERATIVE DISORDERS; HYPEREOSINOPHILIC SYNDROME; FUSION GENE; FIP1L1-PDGFRA; ABNORMALITIES; LEUKEMIA; EFFICACY; MESYLATE;
D O I
10.1038/leu.2013.129
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:2254 / 2256
页数:4
相关论文
共 12 条
  • [1] Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta
    Apperley, JF
    Gardembas, M
    Melo, JV
    Russell-Jones, R
    Bain, BJ
    Baxter, J
    Chase, A
    Chessells, JM
    Colombat, M
    Dearden, CE
    Dimitrijevic, S
    Mahon, FX
    Marin, D
    Nikolova, Z
    Olavarria, E
    Silberman, S
    Schultheis, B
    Cross, NCP
    Goldman, JM
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (07) : 481 - 487
  • [2] The efficacy of imatinib mesylate in patients with FIP1L1-PDGFRα-positive hypereosinophilic syndrome. Results of a multicenter prospective study
    Baccarani, Michele
    Cilloni, Daniela
    Rondoni, Michela
    Ottaviani, Emanuela
    Messa, Francesca
    Merante, Serena
    Tiribelli, Mario
    Buccisano, Francesco
    Testoni, Nicoletta
    Gottardi, Enrico
    de Vivo, Antonio
    Giugliano, Emilia
    Iacobucci, Ilaria
    Paolini, Stefania
    Soverini, Simona
    Rosti, Gianantonio
    Rancati, Francesca
    Astolfi, Cinzia
    Pane, Fabrizio
    Saglio, Giuseppe
    Martinelli, Giovanni
    [J]. HAEMATOLOGICA, 2007, 92 (09) : 1173 - 1179
  • [3] Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1
    Bain, Barbara J.
    [J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (05): : 696 - 698
  • [4] A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
    Cools, J
    DeAngelo, DJ
    Gotlib, J
    Stover, EH
    Legare, RD
    Cortes, J
    Kutok, J
    Clark, J
    Galinsky, I
    Griffin, JD
    Cross, NCP
    Tefferi, A
    Malone, J
    Alam, R
    Schrier, SL
    Schmid, J
    Rose, M
    Vandenberghe, P
    Verhoef, G
    Boogaerts, M
    Wlodarska, I
    Kantarjian, H
    Marynen, P
    Coutre, SE
    Stone, R
    Gilliland, DG
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (13) : 1201 - 1214
  • [5] Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders
    Cross, Nicholas C. P.
    Reiter, Andreas
    [J]. ACTA HAEMATOLOGICA, 2008, 119 (04) : 199 - 206
  • [6] Durable responses to imatinib in patients with PDGFRB fusion gene-positive and BCR-ABL-negative chronic myeloproliferative disorders
    David, Marianna
    Cross, Nicholas C. P.
    Burgstaller, Sonja
    Chase, Andrew
    Curtis, Claire
    Dang, Raymond
    Gardembas, Martine
    Goldman, John M.
    Grand, Francis
    Hughes, George
    Huguet, Francoise
    Lavender, Louise
    McArthur, Grant A.
    Mahon, Francois X.
    Massimini, Giorgio
    Melo, Junia
    Rousselot, Philippe
    Russell-Jones, Robin J.
    Seymour, John F.
    Smith, Graeme
    Stark, Alastair
    Waghorn, Katherine
    Nikolova, Zariana
    Apperley, Jane F.
    [J]. BLOOD, 2007, 109 (01) : 61 - 64
  • [7] Screening for diverse PDGFRA or PDGFRB fusion genes is facilitated by generic quantitative reverse transcriptase polymerase chain reaction analysis
    Erben, Philipp
    Gosenca, Darko
    Mueller, Martin C.
    Reinhard, Jelena
    Score, Joannah
    del Valle, Francesco
    Walz, Christoph
    Mix, Juergen
    Metzgeroth, Georgia
    Ernst, Thomas
    Haferlach, Claudia
    Cross, Nicholas C. P.
    Hochhaus, Andreas
    Reiter, Andreas
    [J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (05): : 738 - 744
  • [8] Five years since the discovery of FIP1L1-PDGFRA: what we have learned about the fusion and other molecularly defined eosinophilias
    Gotlib, J.
    Cools, J.
    [J]. LEUKEMIA, 2008, 22 (11) : 1999 - 2010
  • [9] Durable remission after treatment with very low doses of imatinib for FIP1L1-PDGFRα-positive chronic eosinophilic leukaemia
    Helbig, Grzegorz
    Moskwa, Andrzej
    Hus, Marek
    Piszcz, Jaroslaw
    Swiderska, Alina
    Urbanowicz, Alina
    Calbecka, Malgorzata
    Seferynska, Ilona
    Razny, Malgorzata
    Rodzaj, Marek
    Zuk, Ewa
    Kyrcz-Krzemien, Slawomira
    [J]. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2011, 67 (04) : 967 - 969
  • [10] Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma
    Metzgeroth, G.
    Walz, C.
    Score, J.
    Siebert, R.
    Schnittger, S.
    Haferlach, C.
    Popp, H.
    Haferlach, T.
    Erben, P.
    Mix, J.
    Mueller, M. C.
    Beneke, H.
    Mueller, L.
    Del Valle, F.
    Aulitzky, W. E.
    Wittkowsky, G.
    Schmitz, N.
    Schulte, C.
    Mueller-Hermelink, K.
    Hodges, E.
    Whittaker, S. J.
    Diecker, F.
    Doehner, H.
    Schuld, P.
    Hehlmann, R.
    Hochhaus, A.
    Cross, N. C. P.
    Reiter, A.
    [J]. LEUKEMIA, 2007, 21 (06) : 1183 - 1188