Growth Abnormalities in Children with Type 1 Diabetes, Juvenile Chronic Arthritis, and Asthma

被引：33
作者：
Giannini, Cosimo [1 ,2 ]
Mohn, Angelika [1 ,2 ]
Chiarelli, Francesco [1 ,2 ]
机构：
[1] Univ G dAnnunzio, Osped Policlin, Dept Pediat, I-66100 Chieti, Italy
[2] Univ G dAnnunzio, G DAnnunzio Univ Fdn, Dept Pediat, I-66100 Chieti, Italy
来源：
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY | 2014年 / 2014卷
关键词：
HORMONE-BINDING-PROTEIN; INHALED FLUTICASONE PROPIONATE; RESIDUAL AIRWAYS OBSTRUCTION; FINAL ADULT HEIGHT; FACTOR-I; GLYCEMIC CONTROL; IDIOPATHIC ARTHRITIS; PREPUBERTAL CHILDREN; LINEAR GROWTH; TNF-ALPHA;
D O I：
10.1155/2014/265954
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Children and adolescents with chronic diseases are commonly affected by a variable degree of growth failure, leading to an impaired final height. Of note, the peculiar onset during childhood and adolescence of some chronic diseases, such as type 1 diabetes, juvenile idiopathic arthritis, and asthma, underlines the relevant role of healthcare planners and providers in detecting and preventing growth abnormalities in these high risk populations. In this review article, the most relevant common and diseasespecific mechanisms by which these major chronic diseases affect growth in youth are analyzed. In addition, the available and potential targeting strategies to restore the physiological, hormonal, and inflammatory pattern are described.
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页数：10
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