Cytotoxic properties of leaf essential oil and components from indigenous cinnamon (Cinnamomum osmophloeum Kaneh)

被引:0
|
作者
Huang, TC [1 ]
Ho, CT
Fu, HY
Pan, MH
机构
[1] Natl Pingtung Univ, Dept Food Sci, Pingtung 912, Taiwan
[2] Rutgers State Univ, Dept Food Sci, New Brunswick, NJ 08907 USA
[3] Tajen Inst Technol, Dept Food Sci & Technol, Pingtung 907, Taiwan
[4] Natl Kao Hsiung Marine Univ, Dept Food Sci, Kaohsiung, Taiwan
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中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The essential oils from leaves of three Cinnamomum osmophloeum clones (A, B and C) and their major chemical constituents were investigated. GC and GC-MS analyses showed that Cinnamomum osmophloeum clones A, B and C contain trans-cinnamaldehyde (90.6%), eugenol (91.3%) and linalool (83.7%), respectively, as the major component. The inhibitory effects of the essential oils on the growth of human leukemia cell lines U937 and K562 Hep-1, in vitro were investigated. A strong cell proliferation inhibition activity for Cinnamomum osmophloeum clone A was observed for cell lines K562, whereas Cinnamomum osmophloeum clone B and Cinnamomum osmophloeum clone C gave comparatively low inhibition. This trend paralleled the cytotoxic properties of authentic trans-cinnamaldehyde, eugenol and linalool, respectively.
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页码:299 / 313
页数:15
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