The Development of Technology to Prevent, Diagnose, and Manage Antimicrobial Resistance in Healthcare-Associated Infections

被引:13
作者
Elbehiry, Ayman [1 ,2 ]
Marzouk, Eman [1 ]
Abalkhail, Adil [1 ]
El-Garawany, Yasmine [3 ]
Anagreyyah, Sulaiman [4 ]
Alnafea, Yaser [5 ]
Almuzaini, Abdulaziz M. [6 ]
Alwarhi, Waleed [7 ]
Rawway, Mohammed [8 ,9 ]
Draz, Abdelmaged [6 ]
机构
[1] Qassim Univ, Coll Publ Hlth & Hlth Informat, Dept Publ Hlth, Bukayriyah 52741, Saudi Arabia
[2] Univ Sadat City, Fac Vet Med, Dept Bacteriol Mycol & Immunol, Sadat City 32511, Egypt
[3] Alexandria Univ, Fac Pharm, Clin Pharm Program, Alexandria 21521, Egypt
[4] King Fahad Armed Hosp, Dept Prevent Med, Jeddah 23311, Saudi Arabia
[5] King Fahad Armed Hosp, Dept Stat, Jeddah 23311, Saudi Arabia
[6] Qassim Univ, Coll Agr & Vet Med, Dept Vet Med, Buraydah 52571, Saudi Arabia
[7] King Saud Univ, Coll Sci, Dept Bot & Microbiol, Riyadh 11451, Saudi Arabia
[8] Jouf Univ, Coll Sci, Biol Dept, Sakaka 42421, Saudi Arabia
[9] Al Azhar Univ, Fac Sci, Bot & Microbiol Dept, Assiut 71524, Egypt
关键词
antimicrobial resistance; multidrug-resistant bacteria; rapid detection; alternative therapy; prevention; STAPHYLOCOCCUS-AUREUS; ANTIBIOTIC-RESISTANCE; ESCHERICHIA-COLI; ROUTINE IDENTIFICATION; KLEBSIELLA-PNEUMONIAE; MOLECULAR-MECHANISMS; EXTENDED-SPECTRUM; MICROFLEX LT; VITEK MS; NANOPARTICLES;
D O I
10.3390/vaccines10122100
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
There is a growing risk of antimicrobial resistance (AMR) having an adverse effect on the healthcare system, which results in higher healthcare costs, failed treatments and a higher death rate. A quick diagnostic test that can spot infections resistant to antibiotics is essential for antimicrobial stewardship so physicians and other healthcare professionals can begin treatment as soon as possible. Since the development of antibiotics in the last two decades, traditional, standard antimicrobial treatments have failed to treat healthcare-associated infections (HAIs). These results have led to the development of a variety of cutting-edge alternative methods to combat multidrug-resistant pathogens in healthcare settings. Here, we provide an overview of AMR as well as the technologies being developed to prevent, diagnose, and control healthcare-associated infections (HAIs). As a result of better cleaning and hygiene practices, resistance to bacteria can be reduced, and new, quick, and accurate instruments for diagnosing HAIs must be developed. In addition, we need to explore new therapeutic approaches to combat diseases caused by resistant bacteria. In conclusion, current infection control technologies will be crucial to managing multidrug-resistant infections effectively. As a result of vaccination, antibiotic usage will decrease and new resistance mechanisms will not develop.
引用
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页数:19
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