Functional Imaging to Predict Tumor Response in Locally Advanced Cervical Cancer

被引：44

作者：

Barwick, Tara D. ^{[1
,3
]}

Taylor, Alexandra ^{[2
]}

Rockall, Andrea ^{[1
]}

机构：

[1] Imperial Coll Healthcare NHS Trust, Dept Radiol, London, England

[2] Royal Marsden Hosp Fdn NHS Trust, Dept Clin Oncol, London SW3 6JJ, England

[3] Imperial Coll Healthcare NHS Trust, Dept Imaging, Hammersmith Hosp, London W12 0HS, England

来源：

CURRENT ONCOLOGY REPORTS | 2013年 / 15卷 / 06期

关键词：

Cervical cancer; PET/CT; MRI; Diffusion-weighted imaging; Standardized uptake value; Apparent diffusion coefficient; Response assessment; Functional imaging; POSITRON-EMISSION-TOMOGRAPHY; APPARENT DIFFUSION-COEFFICIENT; STANDARDIZED UPTAKE VALUE; SQUAMOUS-CELL CARCINOMA; RADIATION-THERAPY; UTERINE CERVIX; LYMPH-NODES; F-18; FLUORODEOXYGLUCOSE; METABOLIC-RESPONSE; WEIGHTED MRI;

D O I：

10.1007/s11912-013-0344-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Worldwide, cervical cancer is the third commonest cancer. Prognostic factors for cervical cancer include tumor size, histological subtype, histological grade, International Federation of Gynecology and Obstetrics (FIGO) stage, nodal status and performance status. However these known parameters are not sufficient to accurately predict treatment response or prognosis. There is a clinical need for noninvasive prognostic biomarkers to provide more detailed tumor characterization at the baseline and/or early during therapy, which may permit personalized treatment and potentially improve outcomes. Functional imaging techniques have been developing rapidly over the past decade. Imaging parameters derived from PET/CT and functional MRI techniques are emerging as promising response biomarkers. This review details the current evidence and future potential of functional imaging to predict tumor response in locally advanced cervical carcinoma.

引用

页码：549 / 558

页数：10

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