An outbreak of hepatitis E and high maternal mortality at Port Sudan, Eastern Sudan

被引：61

作者：

Rayis, Duria A. ^{[1
]}

Jumaa, Ammar M. ^{[2
]}

Gasim, Gasim I. ^{[2
]}

Karsany, Mubark S. ^{[3
]}

Adam, Ishag ^{[1
]}

机构：

[1] Univ Khartoum, Fac Med, Khartoum, Sudan

[2] Red Sea Univ, Fac Med, Port Sudan, Sudan

[3] Karary Univ, Coll Med Lab Sci, Khartoum, Sudan

来源：

PATHOGENS AND GLOBAL HEALTH | 2013年 / 107卷 / 02期

关键词：

Pregnancy; Viral hepatitis; Hepatitis E virus; Sudan; E VIRUS-INFECTION; PREGNANT-WOMEN; PERINATAL OUTCOMES; VIRAL-HEPATITIS; TRANSMISSION; SEROPREVALENCE; EPIDEMIOLOGY; PREVALENCE; KASSALA; AFRICA;

D O I：

10.1179/2047773213Y.0000000076

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

During 4 months (November 2010-March 2011) of an outbreak of hepatitis E virus (HEV), 39 pregnant women presented at Port Sudan Hospital, Sudan, with various symptoms of viral hepatitis. The diagnosis of viral hepatitis was confirmed by serology using ELISA anti-HEV IgG and IgM. The mean (SD) maternal age and gestational age were 24.0 (4.2) years and 33.6 (3.7) weeks, respectively. Eight (20.5%) women were primigravidae. There were 11 (28.2%) maternal deaths, 14 (36.0%) intrauterine fetal deaths, and eight (20.5%) cases of postpartum haemorrhage. There were nine (23.0%) cases of preterm (<37 weeks of gestation) deliveries. Fulminant hepatitis with hepatic encephalopathy was the most common cause of death among these patients. Nine of these women died before delivery and the other two died immediately following the delivery due to severe haemorrhage. There were no significant differences in clinical and biochemical data between the women who died (11) and those who survived.

引用

页码：66 / 68

页数：3

共 33 条

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