Molecular docking analysis of aspirin analogues with β-catenin

被引:0
作者
Selvaraj, Jayaraman [1 ]
Sardar, Hussain [2 ]
Visimupriya, Veeraraghavan [1 ]
Balakrishna, Janardhana Papayya [3 ]
Mohan, Surapaneni Krishna [4 ,5 ]
Nivedha, Rajamanickam Pon [6 ]
Vijayalakshmi, Periyasamy [7 ]
Ponnulakshmi, Rajagopal [8 ]
机构
[1] Saveetha Univ, Saveetha Dent Coll & Hosp, Saveetha Inst Med & Tech Sci, Dept Biochem, Chennai 600077, Tamil Nadu, India
[2] Govt Sci Coll, Dept Biotechnol, Chitradurga 577501, Karnataka, India
[3] Stellixir Biotech Pvt Ltd, Dept Stem Cell Biol, V-31,2nd Floor,10th Main Rd,Peenya 2nd Stage Ind, Bangalore 560058, Karnataka, India
[4] Panimalar Med Coll Hosp & Res Inst, Dept Biochem, Chennai 600123, Tamil Nadu, India
[5] Panimalar Med Coll Hosp & Res Inst, Dept Clin Skills & Simulat, Chennai 600123, Tamil Nadu, India
[6] Exonn Biosci, Ticel Bio Pk, Chennai 6000113, Tamil Nadu, India
[7] Holy Cross Coll Autonomous, PG & Res Dept Biotechnol & Bioinformat, Trichy 620002, Tamil Nadu, India
[8] Meenakshi Acad Higher Educ & Res Deemed Be Univ, Cent Res Lab, Chennai 600078, Tamil Nadu, India
关键词
Colon cancer; Wnt signaling; molecular docking; ADME;
D O I
10.6026/97320630016725
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Canonical Wnt signaling pathway plays a crucial role in cancer cell proliferation, which links by the growth of beta-catenin in cell due to inactivation of glycogen synthetase kinase-3. Therefore, it is of interest to design novel candidates to bind with beta-catenin. Hence, we document the molecular docking analysis data of aspirin analogues with beta-catenin for further consideration
引用
收藏
页码:725 / 729
页数:5
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