Dynamical Light Scattering for DNA-CTMA: DR1 chains: Wormlike Semi-Flexible Model, Coil Size and Persistence Length

被引:0
作者
Mitus, A. C. [1 ]
Radosz, W. [1 ]
Pawlik, G. [1 ]
Lazar, C. A. [2 ]
Kajzar, F. [2 ,3 ]
Rau, I. [2 ]
机构
[1] Univ Sci & Technol, Fac Fundamental Problems Technol, Dept Theoret Phys, Wroclaw, Poland
[2] Univ Politehn Bucuresti, Fac Appl Chem & Mat Sci, Bucharest, Romania
[3] Univ Claude Bernard, Chim Lab, CNRS, ENS Lyon, Villeurbanne, France
来源
NANOBIOSYSTEMS: PROCESSING, CHARACTERIZATION, AND APPLICATIONS IX | 2016年 / 9928卷
关键词
DNA; Dynamic Light Scattering; coil size; persistence length; wormlike model;
D O I
10.1117/12.2238000
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Recent experimental Dynamic Light Scattering (DLS) studies of the coil sizes of DNA-CTMA: Rh solutions have lead to numerical discrepancies with theoretical predictions amounting to one-two orders of magnitude. 1 In this paper, which has partially character of a tutorial, we present the basic theoretical concepts underlying an analysis of the polymer coil sizes from DLS experiments. In particular, we discuss the limitations of those methods. We present a wormlike model of a polymer chain which is a promising candidate for inferring information about the spatial structure of the DNA chain from experimental data.
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页数:7
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