Cytokine expression in human labial minor salivary gland epithelial cells in health and disease

被引:24
|
作者
Fox, PC [1 ]
Brennan, M [1 ]
Di Sun, P [1 ]
机构
[1] NIDR, Clin Invest Sect, Gene Therapy & Therapeut Branch, Bethesda, MD 20892 USA
关键词
minor salivary glands; cytokines; Sjogren's syndrome;
D O I
10.1016/S0003-9969(99)00050-3
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Microdissection of biopsy material from labial minor salivary glands followed by RT-PCR demonstrates extensive production of cytokines IL-2, IL-6, IL-10, TNF-alpha, TGF-beta, and IFN-gamma in both normal glands and in glands affected by Sjogren's syndrome. Continuation of these studies should expand our knowledge of normal salivary gland function and the pathogenis of Sjogren'syndrome.
引用
收藏
页码:S49 / S52
页数:4
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