Comparison of absorbable and nonabsorbable sutures for microsurgical vasovasostomy in rats

被引:8
|
作者
Sheynkin, YR
Li, PS
Magid, MLS
Carlson, D
Chen, ECS
Goldstein, M
机构
[1] Cornell Univ, Med Ctr, New York Hosp, Ctr Male Reprod Med & Microsurg,Dept Urol, New York, NY 10021 USA
[2] Cornell Univ, Med Ctr, New York Hosp, Ctr Male Reprod Med & Microsurg,Dept Pathol, New York, NY 10021 USA
[3] Populat Council, Ctr Biomed Res, New York, NY 10021 USA
[4] SUNY Stony Brook, Dept Urol, Stony Brook, NY 11794 USA
关键词
D O I
10.1016/S0090-4295(99)00022-9
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Objectives. At least 12% of initially patent vasovasostomies (Ws) shut down. Currently, only nonabsorbable sutures are used for W. A synthetic, slowly absorbing, monofilament polyglactin suture has been developed that retains tensile strength for up to 6 months. We performed a prospective controlled randomized study comparing absorbable and nonabsorbable sutures for rat Ws. Methods. Bilateral microsurgical W was performed in three groups of 36 Wistar male rats, with 10-0 nylon, 10-0 polypropylene, and 10-0 polyglactin sutures. Twelve control rats underwent sham operations. Three rats in each group were killed at 2, 6, 12, and 24 weeks. The abdominal end of the vas deferens was transected and the intraluminal fluid examined microscopically for presence of sperm. The segment of the vas deferens containing the anastomosis was excised. Fluid from the testicular end was examined for sperm to confirm spermatogenesis. Patency was confirmed by an antegrade indigo carmine vasogram of the anastomotic segment. Segments were randomly sent for histologic or tensile strength evaluation. Results. The mean tensile strength of the anastomoses performed with nylon was slightly higher than in polypropylene and polyglactin sutures, although the difference was not statistically significant. Polyglactin consistently maintained tensile strength throughout 6 months without significant fluctuations. The mean patency rate in the polyglactin group was 96%, in nylon 81%, and in polypropylene 61%. Although polyglactin had a consistently higher patency rate compared with nonabsorbable sutures, the difference was not statistically significant (P = 0.11) but indicated a strong trend. The occurrence of microscopic sperm granuloma, muscle layer injuries, intimal fibrosis, and adventitial fibrosis of the vas deferens was not significantly different between suture types. Conclusions. The three suture materials appear equivalent with respect to overall tensile strength of anastomosis; with histologic evaluation, the trend was toward better patency with polyglactin. Polyglactin 10-0 microsurgical suture is a viable alternative to nonabsorbable sutures in microsurgical Ws, although further studies are indicated to assess long-term results. UROLOGY 53: 1235-1238, 1999. (C) 1999, Elsevier Science Inc. All rights reserved.
引用
收藏
页码:1235 / 1238
页数:4
相关论文
共 50 条
  • [1] Comparison of absorbable and nonabsorbable sutures for microsurgical vasovasostomy (VV) in the rat.
    Sheynkin, YR
    Li, PS
    Magid, MLS
    Carlson, D
    Chen, CS
    Goldstein, M
    JOURNAL OF UROLOGY, 1998, 159 (05): : 205 - 205
  • [2] AORTIC ISTHMUS STENOSIS - COMPARISON OF NONABSORBABLE WITH ABSORBABLE SUTURES
    WOZNIAK, G
    VONSEGESSER, LK
    REAL, F
    TURINA, M
    HELVETICA CHIRURGICA ACTA, 1991, 57 (04) : 655 - 658
  • [3] COMPARISON OF NONABSORBABLE AND ABSORBABLE SUTURES FOR USE IN OCULOPLASTIC SURGERY
    LINBERG, JV
    MANGANO, LM
    ODOM, JV
    OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY, 1991, 7 (01): : 1 - 7
  • [4] ABSORBABLE AND NONABSORBABLE SUTURES IN BRONCHOPLASTY
    SAVIEIRA, V
    NUNES, AC
    PINTO, N
    RAMOS, M
    BULLETIN EUROPEEN DE PHYSIOPATHOLOGIE RESPIRATOIRE-CLINICAL RESPIRATORY PHYSIOLOGY, 1986, 22 : S56 - S56
  • [5] Recurrence of apical prolapse: comparison between absorbable and nonabsorbable sutures
    Schlageter, Fabiola
    Mass-Lindenbaum, Marcelo
    Blumel, Bernardita
    Pizarro-Berdichevsky, Javier
    NEUROUROLOGY AND URODYNAMICS, 2020, 39 : S271 - S271
  • [6] Comparison of Absorbable and Nonabsorbable Sutures for Intradermal Skin Closure in Dogs
    Balomenos, Dimitrios B.
    Gouletsou, Pagona G.
    Galatos, Apostolos D.
    VETERINARY SCIENCES, 2023, 10 (02)
  • [7] Comparison of absorbable and nonabsorbable sutures for intradermal skin closure in cats
    Papazoglou, Lysimachos G.
    Tsioli, Vassiliki
    Papaioannou, Nikolaos
    Georgiadis, Marios
    Savvas, Ioannis
    Prassinos, Nikitas
    Kouti, Vasileia
    Bikiaris, Dimitrios
    Hadzigiannakis, Christos
    Zavros, Nikolaos
    CANADIAN VETERINARY JOURNAL-REVUE VETERINAIRE CANADIENNE, 2010, 51 (07): : 770 - 772
  • [8] COMPARISON BETWEEN ABSORBABLE AND NONABSORBABLE SUTURES IN ARTERIAL ANASTOMOSES IN GROWING DOGS
    GERSAK, B
    JOURNAL OF CARDIOVASCULAR SURGERY, 1991, 32 (06): : 757 - 760
  • [9] Modified Caspari technique for traumatic anterior shoulder instability: Comparison of absorbable sutures versus absorbable plus nonabsorbable sutures
    Kagaya, K
    Yoneda, M
    Hayashida, K
    Wakitani, S
    Nakagawa, S
    Maeda, A
    Izawa, K
    ARTHROSCOPY, 1999, 15 (04): : 400 - 407
  • [10] Comparison of Cosmetic Outcomes of Absorbable Versus Nonabsorbable Sutures in Pediatric Facial Lacerations
    Luck, Raemma
    Tredway, Trevor
    Gerard, James
    Eyal, Dalit
    Krug, Lauren
    Flood, Robert
    PEDIATRIC EMERGENCY CARE, 2013, 29 (06) : 691 - 695