Research of phase transformation induced biodegradable properties on hydroxyapatite and tricalcium phosphate based bioceramic

被引：29

作者：

Chu, Kuo-Tien ^{[1
,2
]}

Ou, Shih-Fu ^{[3
,4
,5
]}

Chen, Shyuan-Yow ^{[6
]}

Chiou, Shi-Yung ^{[3
]}

Chou, Hsin-Hua ^{[1
,7
]}

Ou, Keng-Liang ^{[4
,5
,8
]}

机构：

[1] Taipei Med Univ, Coll Oral Med, Dept Dent, Taipei 110, Taiwan

[2] Taipei Med Univ Hosp, Dept Dent, Div Prosthodont, Taipei 110, Taiwan

[3] Natl Kaohsiung Univ Appl Sci, Dept Mold & Die Engn, Kaohsiung 807, Taiwan

[4] Taipei Med Univ, Res Ctr Biomed Devices & Prototyping Prod, Taipei 110, Taiwan

[5] Taipei Med Univ, Res Ctr Biomed Implants & Microsurg Devices, Taipei 110, Taiwan

[6] Cathay Gen Hosp, Dept Dent, Div Periodont, Taipei 106, Taiwan

[7] Taipei Med Univ, Dept Dent, Div Periodont, Wanfang Hosp, Taipei 116, Taiwan

[8] Taipei Med Univ, Grad Inst Biomed Mat & Tissue Engn, Taipei 110, Taiwan

来源：

CERAMICS INTERNATIONAL | 2013年 / 39卷 / 02期

关键词：

Sintering; alpha-tricalcium phosphate; Hydroxyapatite; Dehydroxylation; CALCIUM-PHOSPHATE; MECHANICAL-PROPERTIES; AUTOGENOUS BONE; ALPHA-TCP; TEMPERATURE; BEHAVIOR; CERAMICS; DENSIFICATION; STRENGTH; DIFFERENTIATION;

D O I：

10.1016/j.ceramint.2012.07.089

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Biodegradable calcium phosphate composites consisting of tricalcium phosphate (alpha-TCP) and hydroxyapatite (HA) were prepared using a two-step sintering method. The ratio of alpha-TCP/HA was controlled by modulating the sintering temperature. The initial calcination process at 800 degrees C causes HA dehydroxylation and induces the early transformation of HA into alpha-TCP in subsequent sintering processes. At the optimum sintering temperature of 1300 degrees C, the material is comprised of a moderate ratio of alpha-TCP to HA (3:7) and possesses a hardness of 5.0 GPa. The high temperature phase transformation from HA to alpha-TCP accompanied by bonded water loss, which results in the formation of nano-pores within the alpha-TCP matrix, hardly deteriorated the mechanical strength of the composite. This pore-containing structure also provided a convincing evidence for the origin of the high degradability of alpha-TCP in a biological environment. (C) 2012 Elsevier Ltd and Techna Group S.r.l. All rights reserved.

引用

页码：1455 / 1462

页数：8

共 57 条

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