A pilot study investigating the effect of transcranial direct current stimulation on the electrophysiological correlates of working memory in patients with schizophrenia

被引：2
作者：
Moon, Sun-Young [1 ]
Kim, Minah [1 ]
Hwang, Wu Jeong [2 ]
Lee, Tae Young [3 ]
Kwon, Jun Soo [1 ,2 ]
机构：
[1] Seoul Natl Univ, Coll Med, Dept Psychiat, 101 Daehak No, Seoul 03080, South Korea
[2] Seoul Natl Univ, Coll Nat Sci, Dept Brain & Cognit Sci, Seoul, South Korea
[3] Seoul Natl Univ Hosp, Dept Neuropsychiat, Seoul, South Korea
来源：
PSYCHIATRY RESEARCH-NEUROIMAGING | 2019年 / 284卷
基金：
新加坡国家研究基金会;
关键词：
Transcranial direct current stimulation (tDCS); Working memory; Event-related potential (ERP); Error-related negativity (ERN); Correct response negativity (CRN); EVENT-RELATED POTENTIALS; METAANALYSIS; TDCS;
D O I：
10.1016/j.pscychresns.2018.12.014
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Transcranial direct current stimulation (tDCS) exerts pro-cognitive effects in various populations. We evaluated the effect of tDCS on cognitive performance and its electrophysiological correlates in schizophrenia patients. Ten participants received 10 sessions of tDCS and performed cognitive performance tasks; error-related negativity and correct response negativity (CRN) were measured before and after tDCS. Verbal performance was improved by tDCS and strongly correlated with a reduced CRN amplitude. Despite the lack of sham control design and possible practice effects of cognitive tasks, we might conclude that CRN could be a modifiable electrophysiological correlate of cognitive improvement by tDCS.
引用
收藏
页码：9 / 12
页数：4
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