Stem Cells for Augmenting Tendon Repair

被引:34
作者
Gulotta, Lawrence V. [1 ]
Chaudhury, Salma [1 ]
Wiznia, Daniel [1 ]
机构
[1] Hosp Special Surg, Sports Med & Shoulder Serv, New York, NY 10021 USA
关键词
MARROW STROMAL CELLS; BONE-MARROW; RABBIT MODEL; DIFFERENTIATION; IMPROVE; MATRIX; IDENTIFICATION; PROLIFERATION; INJURIES;
D O I
10.1155/2012/291431
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Tendon healing is fraught with complications such as reruptures and adhesion formation due to the formation of scar tissue at the injury site as opposed to the regeneration of native tissue. Stem cells are an attractive option in developing cell-based therapies to improve tendon healing. However, several questions remain to be answered before stem cells can be used clinically. Specifically, the type of stem cell, the amount of cells, and the proper combination of growth factors or mechanical stimuli to induce differentiation all remain to be seen. This paper outlines the current literature on the use of stem cells for tendon augmentation.
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页数:7
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