Synthesis of Ethyl 5-(Arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates

被引：4
|
作者：
Hayotsyan, S. S. [1 ]
Sargsyan, A. A. [1 ]
Konkova, S. G. [1 ]
Khachatryan, A. Kh. [1 ,2 ]
Badasyan, A. E. [1 ]
Avagyan, K. A. [1 ]
Panosyan, H. A. [1 ]
Ayvazyan, A. G. [1 ]
Sargsyan, M. S. [1 ]
机构：
[1] Natl Acad Sci Armenia, Sci Technol Ctr Organ & Pharmaceut Chem, Yerevan, Armenia
[2] Minist Emergency Situat Armenia, State Acad Crisis Management, Yerevan, Armenia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 55卷 / 04期
关键词：
cyclization; 1,2-dihydropyridines; Michael adducts; intramolecular cyclization; pyridin-2(1H)-ones;
D O I：
10.1134/S1070428019040080
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one-step procedure has been developed for the synthesis of previously unknown ethyl 5-(arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates by reaction of ethyl 2-cyano-3-ethoxyprop-2-enoate with acetoacetanilides in the presence of a catalytic amount of piperidine in ethanol at room temperature.
引用
收藏
页码：469 / 472
页数：4
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