Synthesis of Ethyl 5-(Arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates

被引：4

作者：

Hayotsyan, S. S. ^{[1
]}

Sargsyan, A. A. ^{[1
]}

Konkova, S. G. ^{[1
]}

Khachatryan, A. Kh. ^{[1
,2
]}

Badasyan, A. E. ^{[1
]}

Avagyan, K. A. ^{[1
]}

Panosyan, H. A. ^{[1
]}

Ayvazyan, A. G. ^{[1
]}

Sargsyan, M. S. ^{[1
]}

机构：

[1] Natl Acad Sci Armenia, Sci Technol Ctr Organ & Pharmaceut Chem, Yerevan, Armenia

[2] Minist Emergency Situat Armenia, State Acad Crisis Management, Yerevan, Armenia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 55卷 / 04期

关键词：

cyclization; 1,2-dihydropyridines; Michael adducts; intramolecular cyclization; pyridin-2(1H)-ones;

D O I：

10.1134/S1070428019040080

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-step procedure has been developed for the synthesis of previously unknown ethyl 5-(arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates by reaction of ethyl 2-cyano-3-ethoxyprop-2-enoate with acetoacetanilides in the presence of a catalytic amount of piperidine in ethanol at room temperature.

引用

页码：469 / 472

页数：4

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