Periodontitis, tooth loss and cognitive functions among older adults

被引:51
作者
Nilsson, Helena [1 ]
Berglund, Johan Sanmartin [2 ,3 ]
Renvert, Stefan [2 ,4 ,5 ]
机构
[1] Halland Hosp, Maxillofacial Unit, S-30185 Halmstad, Sweden
[2] Blekinge Inst Technol, Karlskrona, Sweden
[3] Lund Univ, Dept Clin Sci, Lund, Sweden
[4] Kristianstad Univ, Sch Hlth & Soc, Kristianstad, Sweden
[5] Trinity Coll Dublin, Sch Dent Sci, Dublin, Ireland
关键词
Dementia; Epidemiology; Mild cognitive impairment; Periodontal diseases and tooth loss; ALZHEIMERS-DISEASE; CLOCK TEST; ASSOCIATION; POLYMORPHISMS; POPULATION; IMPAIRMENT; PREVALENCE; SCREEN;
D O I
10.1007/s00784-017-2307-8
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Objectives This study aims to evaluate the potential association between periodontitis, the number of teeth and cognitive functions in a cohort of older adults in Sweden. Materials and methods In total, 775 individuals from 60 to 99 years of age were selected for the study. A clinical and radiographic examination was performed. The number of teeth and prevalence of periodontal pockets and bone loss was calculated and categorised. Cognitive functions were assessed using the Mini-Mental State Examination (MMSE) and clock test. The education level was obtained from a questionnaire. Data were analysed using chi-square tests and multivariate logistic regression. Results Age and gender were associated with the prevalence of bone loss. Age and education were associated with lower number of teeth. Gender was also associated with the presence of pockets. The multivariate logistic regression analysis demonstrated a statistically significant association between prevalence of bone loss, the number of teeth and the outcome on MMSE test. This association remained even after adjustment for age, education and gender. Tooth loss was also associated with lower outcome on clock test. Presence of periodontal pockets >= 5 mm was not associated with cognitive test outcome. Conclusions A history of periodontitis and tooth loss may be of importance for cognitive functions among older adults.
引用
收藏
页码:2103 / 2109
页数:7
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