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A Case of Japanese Encephalitis with a Fatal Outcome in an Australian Who Traveled from Bali in 2019
被引:26
|作者:
Pyke, Alyssa T.
[1
]
Choong, Keat
[2
]
Moore, Frederick
[1
]
Schlebusch, Sanmarie
[1
,3
]
Taylor, Carmel
[1
]
Hewitson, Glen
[1
]
McMahon, Jamie
[1
]
Nair, Neelima
[1
]
Moore, Peter
[1
]
Finger, Mitchell
[1
]
Burtonclay, Peter
[1
]
Wheatley, Sarah
[1
]
机构:
[1] Forens & Sci Serv, Publ Hlth Virol Lab, Coopers Plains, Qld 4108, Australia
[2] Sunshine Coast Univ Hosp, Birtinya, Qld 4575, Australia
[3] Univ Queensland, Sch Med, St Lucia, Qld 4072, Australia
关键词:
Japanese encephalitis;
Japanese encephalitis virus;
flavivirus;
Bali;
Australia;
CSF;
whole genome sequencing;
VIRUS;
HOLIDAY;
D O I:
10.3390/tropicalmed5030133
中图分类号:
R51 [传染病];
学科分类号:
100401 ;
摘要:
A severe case of Japanese encephalitis virus (JEV) infection, resulting in fatality, occurred in an unvaccinated Australian male traveler from Bali, Indonesia, in 2019. During hospitalisation in Australia, patient cerebrospinal fluid (CSF) yielded JEV-specific IgM antibodies and RNA, and an isolate of the virus. Ongoing transmission of JEV in Bali underscores this pathogen as a public health risk and the importance of appropriate health, vaccination and mosquito avoidance advice to prospective travelers to the region.
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