The stress of finding NEMO

被引：21

作者：

Bartek, J

Lukas, J

机构：

[1] Danish Canc Soc, Inst Canc Biol, DK-2100 Copenhagen, Denmark

[2] Danish Canc Soc, Ctr Genotox Stress Res, DK-2100 Copenhagen, Denmark

来源：

SCIENCE | 2006年 / 311卷 / 5764期

关键词：

D O I：

10.1126/science.1124540

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A cell's response to damaged DNA is triggered when two proteins leave the nucleus and converge upon a signaling complex in the cytoplasm. This activates a key transcription factor that then moves into the nucleus to promote cell survival.

引用

页码：1110 / 1111

页数：2

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