Parallels between cerebellum and amygdala-dependent conditioning

被引：193

作者：

Medina, JF ^{[1
]}

Repa, JC ^{[1
]}

Mauk, MD ^{[1
]}

LeDoux, JE ^{[1
]}

机构：

[1] Univ Calif San Francisco, Howard Hughes Med Inst, Dept Physiol, WM Keck Fdn Ctr Intergrat Neurobiol, San Francisco, CA 94143 USA

来源：

NATURE REVIEWS NEUROSCIENCE | 2002年 / 3卷 / 02期

关键词：

D O I：

10.1038/nrn728

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Recent evidence from cerebellum-dependent motor learning and amygdala-dependent fear conditioning indicates that, despite being mediated by different brain systems, these forms of learning might use a similar sequence of events to form new memories. In each case, learning seems to induce changes in two different groups of neurons. Changes in the first class of cells are induced very rapidly during the initial stages of learning, whereas changes in the second class of cells develop more slowly and are resistant to extinction. So, anatomically distinct cell populations might contribute differentially to the initial encoding and the long-term storage of memory in these two systems.

引用

页码：122 / 131

页数：10

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