Utility of the Neonatal Calf Model for Testing Vaccines and Intervention Strategies for Use against Human RSV Infection

被引：23

作者：

Guerra-Maupome, Mariana ^{[1
]}

Palmer, Mitchell V. ^{[2
]}

McGill, Jodi L. ^{[1
]}

Sacco, Randy E. ^{[3
]}

机构：

[1] Iowa State Univ, Dept Vet Microbiol & Preventat Med, Ames, IA 50011 USA

[2] ARS, Infect Bacterial Dis Livestock Res Unit, Natl Anim Dis Ctr, USDA, Ames, IA 50010 USA

[3] ARS, Ruminant Dis & Immunol Res Unit, Natl Anim Dis Ctr, USDA, Ames, IA 50010 USA

来源：

VACCINES | 2019年 / 7卷 / 01期

基金：

美国农业部; 美国国家卫生研究院;

关键词：

RSV; calf model; human; vaccines; therapeutics; RESPIRATORY SYNCYTIAL VIRUS; T-CELL RESPONSES; NONSTRUCTURAL PROTEINS NS1; F NANOPARTICLE VACCINE; BRONCHOALVEOLAR LAVAGE FLUID; NF-KAPPA-B; ANTIBODY-RESPONSE; FUSION GLYCOPROTEIN; INFLAMMATORY CYTOKINES; INTRANASAL VACCINATION;

D O I：

10.3390/vaccines7010007

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Respiratory syncytial virus (RSV) is a significant cause of pediatric respiratory tract infections. It is estimated that two-thirds of infants are infected with RSV during the first year of life and it is one of the leading causes of death in this age group worldwide. Similarly, bovine RSV is a primary viral pathogen in cases of pneumonia in young calves and plays a significant role in bovine respiratory disease complex. Importantly, naturally occurring infection of calves with bovine RSV shares many features in common with human RSV infection. Herein, we update our current understanding of RSV infection in cattle, with particular focus on similarities between the calf and human infection, and the recent reports in which the neonatal calf has been employed for the development and testing of vaccines and therapeutics which may be applied to hRSV infection in humans.

引用

页数：28

共 180 条

[1] PATHOLOGICAL CHANGES IN VIRUS INFECTIONS OF LOWER RESPIRATORY TRACT IN CHILDREN [J].

AHERNE, W ;

BIRD, T ;

COURT, SDM ;

GARDNER, PS ;

MCQUILLIN, J .

JOURNAL OF CLINICAL PATHOLOGY, 1970, 23 (01) :7-+

[2] Epidemiological and genetic characteristics associated with the severity of acute viral bronchiolitis by respiratory syncytial virus [J].

Alvarez, Alfonso E. ;

Marson, Fernando A. L. ;

Bertuzzo, Carmen S. ;

Arns, Clarice W. ;

Ribeiro, Jose D. .

JORNAL DE PEDIATRIA, 2013, 89 (06) :531-543

[3] ANTIGENIC CHARACTERIZATION OF RESPIRATORY SYNCYTIAL VIRUS-STRAINS WITH MONOCLONAL-ANTIBODIES [J].

ANDERSON, LJ ;

HIERHOLZER, JC ;

TSOU, C ;

HENDRY, RM ;

FERNIE, BF ;

STONE, Y ;

MCINTOSH, K .

JOURNAL OF INFECTIOUS DISEASES, 1985, 151 (04) :626-633

[4]

[Anonymous], JUBB KENNEDY PALMERS

[5] Age-dependent differences in the pathogenesis of bovine respiratory syncytial virus infections related to the development of natural immunocompetence [J].

Antonis, Adriaan F. G. ;

de Jong, Marina C. ;

van der Poel, Wim H. M. ;

van der Most, Robbert G. ;

Stockhofe-Zurwieden, Norbert ;

Kimman, Tjeerd ;

Schrijver, Remco S. .

JOURNAL OF GENERAL VIROLOGY, 2010, 91 :2497-2506

[6] Kinetics of antiviral CD8 T cell responses during primary and post-vaccination secondary bovine respiratory syncytial virus infection [J].

Antonis, AFG ;

Claassen, EAW ;

Hensen, EJ ;

de Groot, RJ ;

de Groot-Mijnes, JDF ;

Schrijver, RS ;

Van der Most, RG .

VACCINE, 2006, 24 (10) :1551-1561

[7] Vaccine-induced immunopathology during bovine respiratory syncytial virus infection: Exploring the parameters of pathogenesis [J].

Antonis, AFG ;

Schrijver, RS ;

Daus, F ;

Steverink, PJGM ;

Stockhofe, N ;

Hensen, EJ ;

Langedijk, JPM ;

van der Most, R .

JOURNAL OF VIROLOGY, 2003, 77 (22) :12067-12073

[8] Respiratory syncytial virus infection suppresses IFN-γ production of γδ T cells [J].

Aoyagi, M ;

Shimojo, N ;

Sekine, K ;

Nishimuta, T ;

Kohno, Y .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2003, 131 (02) :312-317

[9] A Phase 2 randomized, observer-blind, placebo-controlled, dose-ranging trial of aluminum-adjuvanted respiratory syncytial virus F particle vaccine formulations in healthy women of childbearing age [J].

August, Allison ;

Glenn, Gregory M. ;

Kpamegan, Eloi ;

Hickman, Somia P. ;

Jani, Dewal ;

Lu, Hanxin ;

Thomas, D. Nigel ;

Wen, Judy ;

Piedra, Pedro A. ;

Fries, Louis F. .

VACCINE, 2017, 35 (30) :3749-3759

[10] Animal models of human respiratory syncytial virus disease [J].

Bem, Reinout A. ;

Domachowske, Joseph B. ;

Rosenberg, Helene F. .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2011, 301 (02) :L148-L156

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