Multistep Enzymatic Synthesis of Long-Chain α,ω-Dicarboxylic and ω-Hydroxycarboxylic Acids from Renewable Fatty Acids and Plant Oils

被引：185

作者：

Song, Ji-Won ^{[1
]}

Jeon, Eun-Yeong ^{[1
]}

Song, Da-Hyun ^{[1
]}

Jang, Hyun-Young ^{[1
]}

Bornscheuer, Uwe T. ^{[2
]}

Oh, Deok-Kun ^{[3
]}

Park, Jin-Byung ^{[1
]}

机构：

[1] Ewha Womans Univ, Dept Food Sci & Engn, Seoul 120750, South Korea

[2] Ernst Moritz Arndt Univ Greifswald, Dept Biotechnol & Enzyme Catalysis, Inst Biochem, D-17487 Greifswald, Germany

[3] Konkuk Univ, Dept Biosci & Biotechnol, Seoul 143701, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 09期

关键词：

biotransformations; carboxylic acids; enzyme catalysis; fatty acids; oxygenation; RECOMBINANT ESCHERICHIA-COLI; BAEYER-VILLIGER MONOOXYGENASE; STENOTROPHOMONAS-MALTOPHILIA; PSEUDOMONAS-FLUORESCENS; 10-HYDROXYSTEARIC ACID; OLEATE HYDRATASE; OLEIC-ACID; REGIOSELECTIVITY; EXPRESSION; CHEMISTRY;

D O I：

10.1002/anie.201209187

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A multistep enzyme catalysis was successfully implemented to produce long-chain α,ω-dicarboxylic and ω-hydroxycarboxylic acids from renewable fatty acids and plant oils. Sebacic acid as well as ω-hydroxynonanoic acid and ω-hydroxytridec-11-enoic acid were produced from oleic and ricinoleic acid. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2534 / 2537

页数：4

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