Stem Cells and Neurological Diseases

被引：0
作者：
Orlacchio, Antonio [1 ,2 ]
Bernardi, Giorgio [1 ,2 ]
Orlacchio, Aldo [3 ]
Martino, Sabata [3 ]
机构：
[1] Ist Ricovero & Cura Carattere Sci IRCCS Santa Luc, CERC, Lab Neurogenet, I-00143 Rome, Italy
[2] Univ Roma Tor Vergata, Dipartimento Neurosci, I-00133 Rome, Italy
[3] Univ Perugia, Dipartimento Med Sperimentale & Sci Biochim, I-06126 Perugia, Italy
来源：
DISCOVERY MEDICINE | 2010年 / 9卷 / 49期
关键词：
HUMAN NEURODEGENERATIVE DISORDERS; AMYOTROPHIC-LATERAL-SCLEROSIS; DOPAMINE NEURONS; THERAPIES; BIOMATERIALS; TRANSPLANTATION; LEUKODYSTROPHY;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The discovery of the therapeutic potential of stem cells offers new opportunities for the treatment of incurable neurological diseases. Based on their biological properties, stem cells act as manufacturers, maintaining the cellular tissue/organ homeostasis in physiological and pathological conditions. Thus, stem cell replacement therapy for central and peripheral nervous system disorders aims at repopulating the affected neural tissue with new neurons, as well as with other neural cells. In this review, we will report on investigations that are raising the promise and the understanding of the challenges behind translating stem cell biology into a novel clinical therapeutic potential for central and peripheral nervous system diseases. [Discovery Medicine 9(49):546-553, June 2010]
引用
收藏
页码：546 / 553
页数：8
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