Green synthesis and characterization of novel 1,2,4,5-tetrasubstituted imidazole derivatives with eco-friendly red brick clay as efficacious catalyst

被引：17

作者：

Kerru, Nagaraju ^{[1
]}

Gummidi, Lalitha ^{[1
]}

Bhaskaruni, Sandeep V. H. S. ^{[1
]}

Maddila, Surya Narayana ^{[1
]}

Jonnalagadda, Sreekantha B. ^{[1
]}

机构：

[1] Univ KwaZulu Natal, Sch Chem & Phys, Westville Campus,Chiltern Hills, ZA-4000 Durban, South Africa

来源：

MOLECULAR DIVERSITY | 2020年 / 24卷 / 04期

关键词：

Red brick clay; Multicomponent; Imidazoles; Aqueous medium; 1; 2; 4-Triazole; ONE-POT SYNTHESIS; IONIC LIQUID; MULTICOMPONENT SYNTHESIS; EFFICIENT; ACID; CHEMISTRY; NANOPARTICLES; METRICS; FACILE; HYDROCARBONS;

D O I：

10.1007/s11030-019-10000-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Use of cheaper and recyclable materials contributes positively to economic growth with environmental sustainability. We report the prospect of utilizing red brick clay as catalyst, which exhibited excellent activity in rapid one-pot four-component condensation of 1,2,4,5-tetrasubstituted imidazoles with high conversion and yields (91-96%) in aqueous medium at 60 degrees C in short reaction times (25-40 min). The red brick clay material was fully characterized by XRD, FT-IR, SEM, TEM, EDX and BET analyses. Red brick clay consisted of oxides of Si (20.38%), Fe (19.55%), Al (14.30%) and minor amounts of Ca (3.60%) and Mg (1.68%). The slate-like-shaped structure morphology and flaky appearance of inexpensive solid clay material proved competent material for the synthesis of 15 novel 1,2,4,5-tetrasubstituted imidazole derivatives. In addition, the advantages of the eco-friendly method are non-toxicity and re-usability of the catalyst. Reaction offers 78% atom economy and 84% carbon capture.

引用

页码：889 / 901

页数：13

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