Septins: cytoskeletal polymers or signalling GTPases?

被引：238
作者：
Field, CM [1 ]
Kellogg, D
机构：
[1] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA
[2] Univ Calif Santa Cruz, Dept Biol, Sinsheimer Labs, Santa Cruz, CA 95064 USA
来源：
TRENDS IN CELL BIOLOGY | 1999年 / 9卷 / 10期
关键词：
D O I：
10.1016/S0962-8924(99)01632-3
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Septins are a family of conserved proteins that have been implicated in a variety of cellular functions involving specialized regions of the cell cortex and changes in cell shape. The biochemistry and localization of septins suggest that they form a novel cytoskeletal system or that they function as scaffolds for the assembly of signalling complexes. This article discusses septin biochemistry and septin-interacting proteins, focusing on the missing link between the structure and biochemical properties of septin proteins, and on how they function at a molecular level in processes such as cytokinesis and yeast budding.
引用
收藏
页码：387 / 394
页数：8
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