Autism and the immune system

被引:0
作者
vanGent, T
Heijnen, CJ
Treffers, PDA
机构
[1] UNIV UTRECHT, NL-3508 TC UTRECHT, NETHERLANDS
[2] LEIDEN UNIV, NL-2300 RA LEIDEN, NETHERLANDS
关键词
autism; immune system; viral infection; autoimmunity;
D O I
暂无
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
As our knowledge of the interactions of the immune, nervous and endocrine systems progresses, complex links with the origin and course of psychopathology in childhood are revealed. In this article the neuroimmunological literature on autism is reviewed. Relevant aspects of immune functioning and the neuroendocrine-immune network. are described. We present the immunological findings in autistic patients within two related conceptual frameworks: a viral and an autoimmune hypothesis. Interpretation of data is hampered by conceptual and methodological differences between studies. Both the clinical significance of the immune changes and the causal connection between immune changes and psychopathological phenomena in autism remain to be elucidated. Recommendations for further research are given.
引用
收藏
页码:337 / 349
页数:13
相关论文
共 50 条
  • [31] Melatonin: Buffering the Immune System
    Carrillo-Vico, Antonio
    Lardone, Patricia J.
    Alvarez-Sanchez, Nuria
    Rodriguez-Rodriguez, Ana
    Guerrero, Juan M.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2013, 14 (04) : 8638 - 8683
  • [32] Immune dysfunction and neuroinflammation in autism spectrum disorder
    Bjorklund, Geir
    Saad, Khaled
    Chirumbolo, Salvatore
    Kern, Janet K.
    Geier, David A.
    Geier, Mark R.
    Urbina, Mauricio A.
    ACTA NEUROBIOLOGIAE EXPERIMENTALIS, 2016, 76 (04) : 257 - 268
  • [33] FOCUS ON: ALCOHOL AND THE IMMUNE SYSTEM
    Molina, Patricia E.
    Happel, Kyle I.
    Zhang, Ping
    Kolls, Jay K.
    Nelson, Steve
    ALCOHOL RESEARCH & HEALTH, 2010, 33 (1-2) : 97 - 108
  • [34] Autism and neuro-immune-gut link
    Siniscalco, Dario
    Brigida, Anna Lisa
    Antonucci, Nicola
    AIMS MOLECULAR SCIENCE, 2018, 5 (02): : 166 - 172
  • [35] Immune Abnormalities in Autism Spectrum Disorder-Could They Hold Promise for Causative Treatment?
    Gladysz, Dominika
    Krzywdzinska, Amanda
    Hozyasz, Kamil K.
    MOLECULAR NEUROBIOLOGY, 2018, 55 (08) : 6387 - 6435
  • [36] Roles of the kallikrein/kinin system in the adaptive immune system
    Schulze-Topphoff, U.
    Prat, A.
    Bader, M.
    Zipp, F.
    Aktas, O.
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2008, 8 (02) : 155 - 160
  • [37] The Timing and Specificity of Prenatal Immune Risk Factors for Autism Modeled in the Mouse and Relevance to Schizophrenia
    McAlonan, Grainne M.
    Li, Qi
    Cheung, Charlton
    NEUROSIGNALS, 2010, 18 (02) : 129 - 139
  • [38] Immune System and Artificial Immune System Application
    Li Chengwei
    Peng Hui
    Xu Aijun
    Wang Shoubin
    WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING 2006, VOL 14, PTS 1-6, 2007, 14 : 477 - +
  • [39] Roles of semaphorins in the immune and hematopoietic system
    Ji, Jong Dae
    Ivashkiv, Lionel B.
    RHEUMATOLOGY INTERNATIONAL, 2009, 29 (07) : 727 - 734
  • [40] Roles of semaphorins in the immune and hematopoietic system
    Jong Dae Ji
    Lionel B. Ivashkiv
    Rheumatology International, 2009, 29 : 727 - 734