Seroprevalence and Risk Factors Associated with Brucellosis as a Professional Hazard in Pakistan

被引：43

作者：

Ali, Shahzad ^{[1
,2
,3
]}

Ali, Qurban ^{[3
]}

Neubauer, Heinrich ^{[2
]}

Melzer, Falk ^{[2
]}

Elschner, Mandy ^{[2
]}

Khan, Iahtasham ^{[2
,4
]}

Abatih, Emmanuel Nji ^{[5
]}

Ullah, Nemat ^{[1
]}

Irfan, Muhammad ^{[1
]}

Akhter, Shamim ^{[1
]}

机构：

[1] Pir Mehr Ali Shah Arid Agr Univ PMAS AAUR, Rawalpindi 46300, Pakistan

[2] Bundesforsch Inst Tiergesundheit, Friedrich Loeffler Inst, Jena, Germany

[3] Natl Vet Labs, Islamabad, Pakistan

[4] Univ Vet & Anim Sci, Lahore, Pakistan

[5] Inst Trop Med, Dept Biomed Sci, Unit Epidemiol & Biostat, B-2000 Antwerp, Belgium

来源：

FOODBORNE PATHOGENS AND DISEASE | 2013年 / 10卷 / 06期

关键词：

OCCUPATIONAL GROUPS; WHOLE-BLOOD; PCR ASSAY; SPP; INDIVIDUALS; PREVALENCE; ANTIBODIES; INFECTION; DIAGNOSIS; ABORTUS;

D O I：

10.1089/fpd.2012.1360

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

The present study was conducted to determine the seroprevalence and identify risk factors associated with brucellosis in humans at high risk in the Potohar plateau of northeastern Pakistan. A total of 262 serum samples were collected from persons of different occupational groups: veterinary personnel, milkers, abattoir workers, livestock farmers, and others (drivers, security guards, housewives). Data related to gender, age, occupation, contact with animals, brucellosis-related symptoms, consumption of raw milk, and geographical region were collected. The Rose Bengal plate test and the serum agglutination test were performed to determine the seroprevalence of brucellosis. The overall seroprevalence was found to be 6.9% (95% confidence interval [CI]: 4.1, 10.6). Real-time polymerase chain reaction assay showed that all cases were affected by Brucella abortus. Individuals who consumed raw milk had higher odds of brucellosis seropositivity. This is the first report of human brucellosis related to B. abortus in high-risk professionals from Pakistan by the combined use of serological and molecular methods.

引用

页码：500 / 505

页数：6

共 34 条

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