The Graceful Exit or Reluctant Demise of the Older Adult With Acute Myeloid Leukemia

被引：5

作者：

Sekeres, Mikkael A. ^{[1
]}

Gerds, Aaron T. ^{[1
]}

机构：

[1] Cleveland Clin, Leukemia Program, Cleveland, OH 44195 USA

来源：

CANCER | 2015年 / 121卷 / 16期

关键词：

LOW-DOSE CYTARABINE; MYELODYSPLASTIC SYNDROME; OUTCOMES; CARE;

D O I：

10.1002/cncr.29428

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Older adults with acute myeloid leukemia should be better prepared for the difficult realities of their disease, and clinicians should adjust their optimism about the potential benefits of induction chemotherapy and practice under the assumption that patients will relapse or that therapy will fail. These patients and their families will then be ready for the health care burden they are about to endure and will be much more open to the suggestion of palliative approaches or hospice when the time comes, recognizing it as part of the natural course of events. © 2015 American Cancer Society.

引用

页码：2678 / 2680

页数：3

共 15 条

[1] A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment [J].

Burnett, Alan K. ;

Milligan, Donald ;

Prentice, Archie G. ;

Goldstone, Anthony H. ;

McMullin, Mary F. ;

Hills, Robert K. ;

Wheatley, Keith .

CANCER, 2007, 109 (06) :1114-1124

[2] Health Care Utilization and End-of-Life Care for Older Patients With Acute Myeloid Leukemia [J].

El-Jawahri, Areej R. ;

Abel, Gregory A. ;

Steensma, David P. ;

LeBlanc, Thomas W. ;

Fathi, Amir T. ;

Graubert, Timothy A. ;

DeAngelo, Daniel J. ;

Wadleigh, Martha ;

Ballen, Karen K. ;

Foster, Julia E. ;

Attar, Eyal C. ;

Amrein, Philip C. ;

Brunner, Andrew M. ;

Stone, Richard M. ;

Temel, Jennifer S. .

CANCER, 2015, 121 (16) :2840-2848

[3]

Eliot TS, 1926, POEMS 1909 1925

[4] Blood transfusions in a day hospice setting [J].

Elyan, Benjamin ;

Hayes, Sally ;

Day, Rebecca ;

Johny, Asha ;

Perkins, Paul .

PALLIATIVE MEDICINE, 2012, 26 (06) :862-863

[5]

Erba Harry P, 2007, Hematology Am Soc Hematol Educ Program, P420

[6]

Estey Elihu H, 2007, Clin Adv Hematol Oncol, V5, P185

[7]

Ferrara F, 2001, HAEMATOLOGICA, V86, P814

[8]

Gerds AT, 2014, BLOOD, V124, P2642

[9] Multicenter, Randomized, Open-Label, Phase III Trial of Decitabine Versus Patient Choice, With Physician Advice, of Either Supportive Care or Low-Dose Cytarabine for the Treatment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia [J].

Kantarjian, Hagop M. ;

Thomas, Xavier G. ;

Dmoszynska, Anna ;

Wierzbowska, Agnieszka ;

Mazur, Grzegorz ;

Mayer, Jiri ;

Gau, Jyh-Pyng ;

Chou, Wen-Chien ;

Buckstein, Rena ;

Cermak, Jaroslav ;

Kuo, Ching-Yuan ;

Oriol, Albert ;

Ravandi, Farhad ;

Faderl, Stefan ;

Delaunay, Jacques ;

Lysak, Daniel ;

Minden, Mark ;

Arthur, Christopher .

JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (21) :2670-2677

[10] High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia [J].

Lowenberg, Bob ;

Ossenkoppele, Gert J. ;

van Putten, Wim ;

Schouten, Harry C. ;

Graux, Carlos ;

Ferrant, Augustin ;

Sonneveld, Pieter ;

Maertens, Johan ;

Jongen-Lavrencic, Mojca ;

von Lilienfeld-Toal, Marie ;

Biemond, Bart J. ;

Vellenga, Edo ;

Kooy, Marinus van Marwijk ;

Verdonck, Leo F. ;

Beck, Joachim ;

Doehner, Hartmut ;

Gratwohl, Alois ;

Pabst, Thomas ;

Verhoef, Gregor .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (13) :1235-1248

← 1 2 →