Highly β-Selective C-Allylation of a Ribofuranoside Controlling Steric Hindrance in the Transition State

被引：15

作者：

Ichikawa, Satoshi ^{[1
]}

Hayashi, Ryoko ^{[1
]}

Hirano, Shinpei ^{[1
]}

Matsuda, Akira ^{[1
]}

机构：

[1] Hokkaido Univ, Fac Pharmaceut Sci, Kita Ku, Sapporo, Hokkaido 0600812, Japan

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 22期

关键词：

D O I：

10.1021/ol8018743

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly beta-selective C-allylation of 2,3-0-(3-pentylidene)-D-ribofuranosyl fluoride is described. This strategy will provide a new concept for synthesizing beta-C-ribosides by controlling the effect of steric hindrance in the transition state.

引用

页码：5107 / 5110

页数：4

共 38 条

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