A simple pathway in preparation of controlled porosity of biphasic calcium phosphate scaffold for dentin regeneration

被引：26

作者：

AbdulQader, Sarah Talib ^{[1
]}

Ab Rahman, Ismail ^{[1
]}

Ismail, Hanafi ^{[2
]}

Kannan, Thirumulu Ponnuraj ^{[1
]}

Mahmood, Zuliani ^{[1
]}

机构：

[1] Univ Sains Malaysia, Sch Dent Sci, Kubang Kerian 16150, Kelantan, Malaysia

[2] Univ Sains Malaysia, Sch Mat & Minerals Resource Engn, Nibong Tebal 14300, Penang, Malaysia

来源：

CERAMICS INTERNATIONAL | 2013年 / 39卷 / 03期

关键词：

Biphasic calcium phosphate; Hydroxyapatite/Beta-tricalcium phosphate; Scaffold; Dentin regeneration; BETA-TRICALCIUM PHOSPHATE; THERMAL-STABILITY; ATOMIC RATIO; IN-VITRO; BONE; HYDROXYAPATITE; FABRICATION; CERAMICS; BIOCERAMICS; APATITES;

D O I：

10.1016/j.ceramint.2012.08.089

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

A simple pathway in preparation of biphasic calcium phosphate scaffold of hydroxyapatite/beta-tricalcium phosphate with controlled pore size, shape and porosity using phosphoric acid and calcium carbonate was successfully developed. Microporosity was controlled by adjusting temperature and soaking time of the sintering process while macroporosity was obtained through addition of polyethylene spherical particles. The advantage of this method is that a highly pure biphasic calcium phosphate scaffold consisting of hydroxyapatite/beta-tricalcium phosphate in a controlled ratio of 20/80 with a mean pore size of 300 mu m and 65% porosity can be produced. These properties of scaffold are of high potential for use in dentin regeneration. (c) 2012 Elsevier Ltd and Techna Group S.r.l. All rights reserved.

引用

页码：2375 / 2381

页数：7

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