Coupling of alkynylTMS derivatives with, vinylic iodides. An efficient route to 1,3-enynes and dienes

被引：61

作者：

Marshall, JA ^{[1
]}

Chobanian, HR ^{[1
]}

Yanik, MM ^{[1
]}

机构：

[1] Univ Virginia, Dept Chem, Charlottesville, VA 22904 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 25期

关键词：

D O I：

10.1021/ol016899m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] CuCl-promoted coupling of alkynylTMS derivatives with vinyl iodides leads to 1,3-enynes in high yield. Enynes prepared! from homopropargylic alcohols undergo intramolecular hydrosilylation and subsequent silyl cleavage with TBAF to afford 1,3-dienes.

引用

页码：4107 / 4110

页数：4

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