Biaryl synthesis via decarboxylative Pd-catalyzed reactions of arenecarboxylic acids and diaryliodonium triflates

被引：132

作者：

Becht, Jean-Michel ^{[1
]}

Le Drian, Claude ^{[1
]}

机构：

[1] Univ Haute Alsace, Ecole Natl Super Chim, CNRS, UMR 7015,Lab Chim Organ & Bioorgan, F-68093 Mulhouse, France

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 14期

关键词：

D O I：

10.1021/ol8011293

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel simple and efficient synthesis of biaryls via a Pd-catalyzed decarboxylative cross-coupling reaction of arenecarboxylic acids and diaryliodonium triflates is described. The PdCl2/DPEphos catalytic system in the presence of Ag2CO3 in DMSO was found to be the most efficient. Various biaryls, including sterically hindered biaryls, were synthesized with yields ranging from 37 to 85%.

引用

页码：3161 / 3164

页数：4

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