Common and distinct neural correlates of obsessive-compulsive and related disorders

被引:103
作者
Mataix-Cols, David
van den Heuvel, Odile A.
机构
[1] Kings Coll London, Inst Psychiat, Dept Psychol Med, London SE5 8AF, England
[2] Kings Coll London, Inst Psychiat, Dept Psychol, London SE5 8AF, England
[3] Vrije Univ Amsterdam Med Ctr, Dept Psychiat, GGZ Buitenamstel, NL-1081 HJ Amsterdam, Netherlands
关键词
D O I
10.1016/j.psc.2006.02.006
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Obsessive-compulsive disorder (OCD) often co-occurs with other anxiety disorders and a number of other disorders of similar phenomenology known as the "OCD spectrum" disorders. Neurobiologically, it is unclear how all these disorders relate to each other. The picture is further complicated by the clinical heterogeneity of OCD itself. This article reviews the literature on the common and distinct neural correlates of OCD, its symptom dimensions, and other anxiety and OCD spectrum disorders with the hope of providing a conceptual and heuristic framework to help understand the relationship between these phenomena.
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页码:391 / +
页数:21
相关论文
共 77 条
  • [1] PARALLEL ORGANIZATION OF FUNCTIONALLY SEGREGATED CIRCUITS LINKING BASAL GANGLIA AND CORTEX
    ALEXANDER, GE
    DELONG, MR
    STRICK, PL
    [J]. ANNUAL REVIEW OF NEUROSCIENCE, 1986, 9 : 357 - 381
  • [2] AMYGDALO-CORTICAL PROJECTIONS IN THE MONKEY (MACACA-FASCICULARIS)
    AMARAL, DG
    PRICE, JL
    [J]. JOURNAL OF COMPARATIVE NEUROLOGY, 1984, 230 (04) : 465 - 496
  • [3] Connections underlying the synthesis of cognition, memory, and emotion in primate prefrontal cortices
    Barbas, H
    [J]. BRAIN RESEARCH BULLETIN, 2000, 52 (05) : 319 - 330
  • [4] fMRI reveals amygdala activation to human faces in social phobics
    Birbaumer, N
    Grodd, W
    Diedrich, O
    Klose, U
    Erb, M
    Lotze, M
    Schneider, F
    Weiss, U
    Flor, H
    [J]. NEUROREPORT, 1998, 9 (06) : 1223 - 1226
  • [5] Caudate volumes in childhood predict symptom severity in adults with Tourette syndrome
    Bloch, MH
    Leckman, JF
    Zhu, HT
    Peterson, BS
    [J]. NEUROLOGY, 2005, 65 (08) : 1253 - 1258
  • [6] Breiter HC, 1996, ARCH GEN PSYCHIAT, V53, P595
  • [7] Amygdala responses to human faces in obsessive-compulsive disorder
    Cannistraro, PA
    Wright, CI
    Wedig, MM
    Martis, B
    Shin, LM
    Wilhelm, S
    Rauch, SL
    [J]. BIOLOGICAL PSYCHIATRY, 2004, 56 (12) : 916 - 920
  • [8] Cannistraro Paul A, 2003, Psychopharmacol Bull, V37, P8
  • [9] SPECT imaging of body dysmorphic disorder
    Carey, P
    Seedat, S
    Warwick, J
    van Heerden, B
    Stein, DJ
    [J]. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 2004, 16 (03) : 357 - 359
  • [10] FRONTAL-SUBCORTICAL CIRCUITS AND HUMAN-BEHAVIOR
    CUMMINGS, JL
    [J]. ARCHIVES OF NEUROLOGY, 1993, 50 (08) : 873 - 880