A new isobenzofuranone from the mangrove endophytic fungus Penicillium sp (ZH58)

被引：19
作者：
Yang, Jianxiang [1 ,2 ]
Huang, Riming [1 ]
Qiu, Sheng Xiang [1 ]
She, Zhigang [2 ]
Lin, Yongcheng [2 ]
机构：
[1] Chinese Acad Sci, South China Bot Garden, Lab Nat Prod Chem, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2013年 / 27卷 / 20期
基金：
中国国家自然科学基金; 美国国家科学基金会;
关键词：
isobenzofuranone; Penicillium sp; mangrove endophytic fungus; PESTALOTIOPSIS-MICROSPORA; NMR ASSIGNMENTS; ANTI-HIV; DERIVATIVES; ANTIOXIDANT; AGENTS;
D O I：
10.1080/14786419.2013.784870
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new isobenzofuranone, 4-(methoxymethyl)-7-methoxy-6-methyl-1(3H)-isobenzofuranone (1), together with seven known compounds, dilation (2), lumichrome (3), curvulari (4), 5,5-oxy-dimethylene-bis(2-furaldehyde) (5), chromone (6), harman(1-methyl--carboline) (7), N9-methyl-1methyl--carboline (8), was isolated from the mangrove endophytic fungus, Penicillium sp. ZH58 obtained from the South China Sea coast. Their structures were determined by analysis of spectroscopic data. Compound 1 exhibited cytotoxicity against KB and KBV200 cells with IC50 values of 6 and 10g/mL, respectively.
引用
收藏
页码：1902 / 1905
页数：4
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