Relaying stereochemistry through aromatic ureas: 1,9 and 1,15 remote stereocontrol

被引：24

作者：

Clayden, Jonathan ^{[1
]}

Pickworth, Mark ^{[1
]}

Jones, Lyn H. ^{[2
]}

机构：

[1] Univ Manchester, Sch Chem, Manchester M13 9PL, Lancs, England

[2] Pfizer Ltd, Sandwich CT12 3NT, Kent, England

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 05期

关键词：

ENANTIOSELECTIVE SYNTHESIS; CONFORMATIONAL PREFERENCE; SUBSTITUTED ARYLUREAS; ATROPISOMERIC AMIDES; ASYMMETRIC-SYNTHESIS; N; N'-DIARYLUREAS; COMMUNICATION; LITHIATION; REDUCTION; CENTERS;

D O I：

10.1039/b817527f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The well-defined conformation of an N,N'-diarylurea allows a chiral sulfinyl substituent to influence diastereoselectivity in the formation of new stereogenic centres up to 14 bond lengths away.

引用

页码：547 / 549

页数：3

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