Cycloadditions of 1,1-Disubstituted Benzocyclobutenes Obtained by C(sp3)-H Activation

被引：22

作者：

Chaumontet, Manon ^{[2
]}

Retailleau, Pascal ^{[2
]}

Baudoin, Olivier ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS, UMR5426, Inst Chim & Biochim Mol & Supramol, F-69622 Villeurbanne, France

[2] Inst Chim Subst Nat, CNRS, UPR2301, F-91198 Gif Sur Yvette, France

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 04期

关键词：

C-H ACTIVATION; ORTHO-QUINODIMETHANES;

D O I：

10.1021/jo802471u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of polycyclic molecules has been performed by a sequence involving palladium-catalyzed C-H activation and [4 + 2] cycloaddition. The intermediate benzocyclobutenes underwent a microwave-enhanced electrocyclic ring-opening/cycloaddition process with complete torquoselectivity and diastereoselectivity.

引用

页码：1774 / 1776

页数：3

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