Is maternal height a risk factor for breast cancer?

被引:5
作者
Lagiou, Pagona [1 ,2 ]
Trichopoulos, Dimitrios [2 ]
Hsieh, Chung-Cheng [2 ,3 ]
机构
[1] Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, GR-11527 Athens, Greece
[2] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[3] Univ Massachusetts, Sch Med, UMass Canc Ctr, Dept Canc Biol, Worcester, MA USA
关键词
birth size; birth weight; breast cancer; fetal growth; height; maternal height; UMBILICAL-CORD BLOOD; BIRTH-WEIGHT; IN-UTERO; STEM; HYPOTHESIS; LACTATION; HEALTH; WOMEN; AGE;
D O I
10.1097/CEJ.0b013e32835b6a82
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We hypothesize that the link between height and the risk of breast cancer may, to some extent, be accounted for by an association between maternal height and the risk of breast cancer. Unlike mothers of smaller stature, among taller mothers, maternal size does not impose constraints on fetal growth, thus allowing growth-enhancing pregnancy hormones, including estriol and insulin-like growth factors, to exercise their growth potential and be positively associated with birth size and, thus, the risk of breast cancer. (C) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
引用
收藏
页码:389 / 390
页数:2
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