Treatment Modification of Yttrium-90 Radioembolization Based on Quantitative Positron Emission Tomography/CT Imaging

被引:17
作者
Chang, Ted T. [1 ]
Bourgeois, Austin C. [1 ]
Balius, Anastasia M. [1 ]
Pasciak, Alexander S. [1 ,2 ]
机构
[1] Univ Tennessee, Grad Sch Med, Dept Radiol, Knoxville, TN 37920 USA
[2] Univ Tennessee, Med Ctr, Dept Radiol, Knoxville, TN 37920 USA
关键词
HEPATOCELLULAR-CARCINOMA; PARTITION MODEL; LIVER-CANCER; MICROSPHERES; THERAPY; ALBUMIN;
D O I
10.1016/j.jvir.2012.12.005
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Treatment activity for yttrium-90 (Y-90) radioembolization when-calculated by Using the manufacturer:recommended technique is only partially patient-specific and may result in a subtumoricidal dose in some patients. The authors describe the use of quantitative Y-90 positron emission tomography/computed tomography as a tool to provide patient-specific optimization of treatment activity and evaluate this new method in a patient who previously received traditional 90Y radioembolization. The modified treatment resulted in a 40-Gy increase in absorbed dose to tumor and complete resolution of disease in the treated area within 3 months.
引用
收藏
页码:333 / 337
页数:5
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