Thioethers as Directing Group for the Palladium-Catalyzed Direct Arylation of Arenes

被引：66

作者：

Yao, Jinzhong ^{[1
]}

Yu, Ming ^{[1
]}

Zhang, Yuhong ^{[1
,2
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Zhejiang, Peoples R China

[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2012年 / 354卷 / 17期

关键词：

arylation; C-H bond activation; palladium; potassium organotrifluoroborates; thioethers; C-H BONDS; CROSS-COUPLING REACTIONS; CARBON-HYDROGEN BONDS; ARYL CHLORIDES; BORONIC ACIDS; ARYLBORON REAGENTS; METAL-COMPLEXES; SUZUKI; ACTIVATION; HALIDES;

D O I：

10.1002/adsc.201200447

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Thioethers have proven to be efficient directing groups for the arylation of arenes under palladium catalysis. The thioether group can be readily removed or converted to other functional groups. Kinetic isotopic effect studies reveal that the C-H cleavage of arenes might be the turnover-limiting step.

引用

页码：3205 / 3210

页数：6