Differences of Ankle-Brachial Index according to Ischemic Stroke Subtypes: The Peripheral Artery Disease in Korean Patients with Ischemic Stroke (PIPE) Study

被引：7

作者：

Chung, Pil-Wook ^{[1
]}

Kim, Dae-Hyun ^{[2
]}

Kim, Hahn Young ^{[3
]}

Park, Kwang-Yeol ^{[4
]}

Park, Tai Hwan ^{[5
]}

Hong, Ji Man ^{[6
]}

Kim, Gyeong-Moon ^{[7
]}

Bang, Oh Young ^{[7
]}

Oh, Kyungmi ^{[8
]}

Lee, Soo Joo ^{[9
]}

机构：

[1] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Dept Neurol, Seoul, South Korea

[2] Dong A Univ, Dept Neurol, Coll Med, Pusan, South Korea

[3] Konkuk Univ, Sch Med, Dept Neurol, Seoul, South Korea

[4] Chung Ang Univ, Coll Med, Dept Neurol, Med Ctr, Seoul 156756, South Korea

[5] Seoul Med Ctr, Dept Neurol, Seoul, South Korea

[6] Ajou Univ, Sch Med, Dept Neurol, Suwon 441749, South Korea

[7] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul, South Korea

[8] Korea Univ, Med Ctr, Dept Neurol, Seoul, South Korea

[9] Eulji Univ, Sch Med, Eulji Univ Hosp, Dept Neurol, Taejon 302799, South Korea

来源：

EUROPEAN NEUROLOGY | 2013年 / 69卷 / 03期

关键词：

Ankle-brachial index; Ischemic stroke; Stroke subtype; PREDICT CARDIOVASCULAR EVENTS; RISK-FACTORS; MYOCARDIAL-INFARCTION; ACUTE CORONARY; DEATH; ATHEROSCLEROSIS; PREVALENCE; MORTALITY; SCORE;

D O I：

10.1159/000342892

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background/Aims: Although previous studies showed a high prevalence of abnormal ankle-brachial index (ABI) in patients with ischemic stroke, few data exist regarding ABI in Asian patients with ischemic stroke. The purpose of the present study was to determine the prevalence and factors associated with abnormal ABI (<= 0.9) in a cohort of ischennic stroke patients. Methods: In this prospective multicenter study, 1,293 patients diagnosed with acute ischennic stroke or transient ischemic attack underwent ABI measurement to evaluate an association between abnormal ABI and vascular risk factors and clinical characteristics. Differences in ABI by stroke subtypes were also assessed. Results: Abnormal ABI of <= 0.9 was found in 13.0%. Patients with abnormal ABI were more likely to be older and had higher initial stroke severity. The prevalence of abnormal ABI was 18.4% in large artery atherosclerosis, 7% in small artery disease, and 19.2% in cardioembolism (p < 0.001). Multiple logistic regression analysis showed that age, hyperlipidemia, diabetes, and large artery atherosclerosis subtype were independent factors associated with abnormal ABI. Conclusions:These data suggest that the prevalence of abnormal ABI in Korean patients with ischemic stroke was lower than that in Caucasian patients, which might be associated with ethnic differences in underlying stroke subtypes. Copyright (C) 2012 S. Karger AG, Basel

引用

页码：179 / 184

页数：6

共 23 条

[1] Subclinical peripheral arterial disease and incompressible ankle arteries are both long-term prognostic factors in patients undergoing coronary artery bypass grafting [J].