Synthesis and neurotropic activity of condensed thieno[2,3e][1,2,4]triazolo[4,3-c]pyrimidine derivatives

被引：5

作者：

Paronikyan, E. G. ^{[1
]}

Akopyan, Sh. F. ^{[1
]}

Noravyan, A. S. ^{[1
]}

Dzhagatspanyan, I. A. ^{[1
]}

Paronikyan, R. G. ^{[1
]}

Nazaryan, I. M. ^{[1
]}

Akopyan, A. G. ^{[1
]}

机构：

[1] Natl Acad Sci Republ Armenia, Inst Fine Organ Chem, Sci Tech Ctr Organ & Pharmaceut Chem, Erevan, Armenia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2012年 / 46卷 / 03期

关键词：

pyrido[2,3-b]thieno[3,2-d]thiazolo(thiazino, thiazepino)[3,2-a]pyrimidines; pyrimido[4 ',5 ':4,5]thieno[2,3-c]isoquinolines; cyclopenta[4 ',5 ']pyrido[3 ',2 ':4,5]thieno[3,2-d]pyrimidines; anticonvulsive activity; ELEVATED PLUS-MAZE;

D O I：

10.1007/s11094-012-0750-z

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

We report the development of methods for the preparation of new heterosystems - condensed pyrano[4aEuro(3),3aEuro(3):4',5']pyrido[3',2':4,5]thieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidines, [1,2,4]triazolo[3aEuro(3),4aEuro(3):6',1']pyrimido[4',5':4,5]thieno[2,3]isoquinolones, and cyclopenta[4',5']pyrido[3',2':4,5]thieno[2,3-e][1,2,4]triazolo [4,3-c]pyrimidines. The anticonvulsive activity of these compounds was studied.

引用

页码：154 / 156

页数：3

共 8 条

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