Ventilation in acute respiratory distress. Lung-protective strategies

被引：3

作者：

Bruells, C. S. ^{[1
]}

Rossaint, R. ^{[1
]}

Dembinski, R. ^{[2
]}

机构：

[1] Rhein Westfal TH Aachen, Anasthesiol Klin, Univ Klinikum, D-52074 Aachen, Germany

[2] Klinikum Bremen Mitte, Klin Intens Med & Notfallmed, Bremen, Germany

来源：

MEDIZINISCHE KLINIK-INTENSIVMEDIZIN UND NOTFALLMEDIZIN | 2012年 / 107卷 / 08期

关键词：

Acute respiratory distress syndrome; Lung-protective ventilation; Pulmonary gas exchange; Recruitment; Respiratory muscle weakness; END-EXPIRATORY PRESSURE; FREQUENCY OSCILLATORY VENTILATION; RANDOMIZED CONTROLLED-TRIAL; TIDAL VOLUMES; INJURY; TOMOGRAPHY; ADULTS; HYPERINFLATION; REVERSIBILITY; RECRUITMENT;

D O I：

10.1007/s00063-012-0130-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Ventilation of patients suffering from acute respiratory distress syndrome (ARDS) with protective ventilator settings is the standard in patient care. Besides the reduction of tidal volumes, the adjustment of a case-related positive end-expiratory pressure and preservation of spontaneous breathing activity at least 48 h after onset is part of this strategy. Bedside techniques have been developed to adapt ventilatory settings to the individual patient and the different stages of ARDS. This article reviews the pathophysiology of ARDS and ventilator-induced lung injury and presents current evidence-based strategies for ventilator settings in ARDS.

引用

页码：596 / 602

页数：7

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