Quantitative analysis via Surface Enhanced Raman Scattering from Ag nano-colloids utilizing an oscillating cell and right-angle collection geometry

被引:16
作者
Manikas, Anastasios C. [1 ,2 ]
Beobide, Amaia Soto [1 ,2 ]
Voyiatzis, George A. [1 ,2 ]
机构
[1] Fdn Res & Technol Hellas, Inst Chem Engn & High Temp Chem Proc ICE HT, GR-26504 Rion, Greece
[2] Univ Patras, Interdepartmental Program Grad Studies Polymer, GR-26500 Patras, Greece
关键词
SINGLE-MOLECULE DETECTION; FLOW-INJECTION ANALYSIS; ORAL FLUID; SPECTROSCOPY; SERS; ORIENTATION; SILVER; NANOPARTICLES; SPECTROMETRY; ADSORPTION;
D O I
10.1039/b815053b
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We examine the application of an oscillating cell in combination with right-angle Raman scattered light collection geometry for quantitative Surface Enhanced (Resonance) Raman Scattering (SER(R) S) measurements from nano-colloidal noble metal solutions. This excitation/collection Raman configuration allows specific SERS and SERRS signatures of aqueous solutions of mitoxantrone, an antitumor drug, to be easily resolved at (sub)-ng/mL and (sub)-pg/mL concentration levels. A partial least-squares (PLS) chemometric algorithm was applied to predict the concentration of 25 mL of aqueous solutions of mitoxantrone added in 0.5 mL of a silver colloidal solution in a test tube attached to the oscillating cell. For SERS (514.5 nm) measurements, this was performed over the range from 0 to 13 ng/mL with a correlation coefficient R-2 of 98.5% and RMS error of prediction equal to 0.5 ng/mL. SERRS (632.8 nm) measurements performed over a range of 0 to 7 pg/mL gave R-2 = 98.92% and RMSE = 0.2 pg/mL.
引用
收藏
页码:587 / 592
页数:6
相关论文
共 33 条
  • [1] ANOMALOUSLY INTENSE RAMAN-SPECTRA OF PYRIDINE AT A SILVER ELECTRODE
    ALBRECHT, MG
    CREIGHTON, JA
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (15) : 5215 - 5217
  • [2] Correlation of Molecular Orientation and Packing Density in a dsDNA Self-Assembled Monolayer Observable with Surface-Enhanced-Raman Spectroscopy
    Barhoumi, Aoune
    Zhang, Dongmao
    Halas, Naomi J.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (43) : 14040 - +
  • [3] Quantitative surface-enhanced Raman spectroscopy of dipicolinic acid - towards rapid anthrax endospore detection
    Bell, SEJ
    Mackle, JN
    Sirimuthu, NMS
    [J]. ANALYST, 2005, 130 (04) : 545 - 549
  • [4] Rapid, quantitative analysis of ppm/ppb nicotine using surface-enhanced Raman scattering from polymer-encapsulated Ag nanoparticles (gel-colls)
    Bell, SEJ
    Sirimuthu, NMS
    [J]. ANALYST, 2004, 129 (11) : 1032 - 1036
  • [5] SURFACE ENHANCED RAMAN-SPECTROMETRY ON SILVER HYDROSOLS STUDIED BY FLOW-INJECTION ANALYSIS
    BERTHOD, A
    LASERNA, JJ
    WINEFORDNER, JD
    [J]. APPLIED SPECTROSCOPY, 1987, 41 (07) : 1137 - 1141
  • [6] Raman spectroscopy of cemented cobalt on zinc substrates
    Bockman, O
    Ostvold, T
    Voyiatzis, GA
    Papatheodorou, GN
    [J]. HYDROMETALLURGY, 2000, 55 (01) : 93 - 105
  • [7] CHARLES F, 2007, EXP REV PROT, V4, P329
  • [8] Oral fluid as a diagnostic tool
    Choo, RE
    Huestis, MA
    [J]. CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2004, 42 (11) : 1273 - 1287
  • [9] Single-molecule detection of yeast cytochrome c by surface-enhanced Raman spectroscopy
    Delfino, I
    Bizzarri, AR
    Cannistraro, S
    [J]. BIOPHYSICAL CHEMISTRY, 2005, 113 (01) : 41 - 51
  • [10] SERS studies of self-assembled DNA monolayer - characterization of adsorption orientation of oligonucleotide probes and their hybridized helices on gold substrate
    Dong, LQ
    Zhou, JZ
    Wu, LL
    Dong, P
    Lin, ZH
    [J]. CHEMICAL PHYSICS LETTERS, 2002, 354 (5-6) : 458 - 465