Metal catalyzed diazo transfer for the synthesis of azides from amines

被引：333

作者：

Alper, PB ^{[1
]}

Hung, SC ^{[1
]}

Wong, CH ^{[1
]}

机构：

[1] Scripps Res Inst, DEPT CHEM, LA JOLLA, CA 92037 USA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 34期

关键词：

D O I：

10.1016/0040-4039(96)01307-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An improved method for the synthesis of a tides is described. Diazo transfer from triflyl azide occurs effectively with Cu++ Ni++ or Zn++ as a catalyst The process is amenable to scaleup, can be carried out using commercially available reagents and does not require anhydrous conditions. When metals are scavenged from the reaction, the rate drops by many orders of magnitude. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6029 / 6032

页数：4

共 8 条

[1]

BUSCAS T, 1994, TETRAHEDRON-ASYMMETR, V5, P2187

[2] TRIFLUOROMETHANESULFONYL AZIDE - ITS REACTION WITH ALKYL AMINES TO FORM ALKYL AZIDES [J].