MetaRanker 2.0: a web server for prioritization of genetic variation data

被引：21

作者：

Pers, Tune H. ^{[1
,2
,3
,4
]}

Dworzynski, Piotr ^{[1
]}

Thomas, Cecilia Engel ^{[1
]}

Lage, Kasper ^{[1
,4
,5
,6
,7
]}

Brunak, Soren ^{[1
,5
]}

机构：

[1] Tech Univ Denmark, Dept Syst Biol, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark

[2] Childrens Hosp Boston, Div Endocrinol, Boston, MA USA

[3] Childrens Hosp Boston, Ctr Basic & Translat Obes Res, Boston, MA USA

[4] Broad Inst Massachusetts Inst Technol & Harvard, Cambridge, MA USA

[5] Univ Copenhagen, Fac Hlth Sci, NNF Ctr Prot Res, Copenhagen, Denmark

[6] Massachusetts Gen Hosp, Pediat Surg Res Labs, Boston, MA 02114 USA

[7] Harvard Univ, Sch Med, Boston, MA USA

来源：

NUCLEIC ACIDS RESEARCH | 2013年 / 41卷 / W1期

关键词：

GENOME-WIDE ASSOCIATION; CANDIDATE GENES; VARIANTS; NETWORK; LOCI;

D O I：

10.1093/nar/gkt387

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

MetaRanker 2.0 is a web server for prioritization of common and rare frequency genetic variation data. Based on heterogeneous data sets including genetic association data, protein-protein interactions, large-scale text-mining data, copy number variation data and gene expression experiments, MetaRanker 2.0 prioritizes the protein-coding part of the human genome to shortlist candidate genes for targeted follow-up studies. MetaRanker 2.0 is made freely available at www.cbs.dtu.dk/services/MetaRanker-2.0.

引用

页码：W104 / W108

页数：5

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