Measurement of IGF-1 and reference ranges

被引：0

作者：

Spilcke-Liss, Elisabeth ^{[1
]}

Friedrich, Nele ^{[1
]}

Wallaschofski, Henri ^{[1
]}

机构：

[1] Ernst Moritz Arndt Univ Greifswald, Klin Innere Med Endokrinol A, D-17487 Greifswald, Germany

来源：

LABORATORIUMSMEDIZIN-JOURNAL OF LABORATORY MEDICINE | 2008年 / 32卷 / 01期

关键词：

growth hormone; insulin-like growth factor I (IGF-1); reference range;

D O I：

10.1515/JLM.2008.001

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Insulin-like growth factor I (IGF-1) represents the key marker for the evaluation of growth hormone (GH) status. A large number of determinants, including age, gender, genetic factors, nutrition and disease states, influence IGF-1 serum levels. Accurate normative data are essential to translate patient data into diagnostic meaning or even use IGF-1 levels for adequate monitoring of patients with an over- or underactive GH axis. Even though reference ranges have been developed in large cohorts of healthy subjects, the dependency of these data on a given assay technology argues for assay specific normative data for IGF-1.

引用

页码：11 / 15

页数：5

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