Palladium catalyzed regioselective mono-alkenylation of o-carboranes via Heck type coupling reaction of a cage B-H bond

被引：54
作者：
Wu, Ji [1 ]
Cao, Ke [1 ]
Xu, Tao-Tao [1 ]
Zhang, Xiao-Juan [1 ]
Jiang, Linhai [1 ]
Yang, Junxiao [1 ]
Huang, Yawen [1 ]
机构：
[1] Southwest Univ Sci & Technol, Sch Mat Sci & Engn, State Key Lab Cultivat Base Nonmet Composite & Fu, Mianyang, Peoples R China
来源：
RSC ADVANCES | 2015年 / 5卷 / 111期
关键词：
MEDICINAL CHEMISTRY; DRUG DISCOVERY; BORON; SUBSTITUTION; COMPLEXES; MOLECULES;
D O I：
10.1039/c5ra18555f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A regioselective mono-alkenylation of o-carboranes on B(8) and B(9) via palladium catalyzed Heck type coupling of a cage B-H bond has been developed, and kinds of B(8)/B(9)-alkenyl-o-carboranes decorated with active groups have been synthesized withmoderate yield as well as good regioselectivity. A PdII catalyzed electrophilic B-H activation mechanism was also proposed.
引用
收藏
页码：91683 / 91685
页数：3
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