Rhodium-Catalyzed Intermolecular [2+2] Cycloaddition of Terminal Alkynes with Electron-Deficient Alkenes

被引：58

作者：

Sakai, Kazunori ^{[1
]}

Kochi, Takuya ^{[1
]}

Kakiuchi, Fumitoshi ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 05期

关键词：

DIMETHYL ACETYLENEDICARBOXYLATE; CYCLOBUTANE DERIVATIVES; ESTERS; COMPLEXES; VINYLIDENE; NORBORNENES; ALKYLIDENE; PROPIOLATE; REACTIVITY; ENYNES;

D O I：

10.1021/ol303510k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first catalytic intermolecular [2 + 2] cycloaddition of terminal alkynes with electron-deficient alkenes is reported. The reaction proceeds with an 8-quinolinolato rhodium/phosphine catalyst system to give cyclobutenes from various substrates having polar functional groups in high yields with complete regioselectivity.

引用

页码：1024 / 1027

页数：4

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