A Ratiometric Fluorescent On-Off Zn2+ Chemosensor Based on a Tripropargylamine Pyrene Azide Click Adduct

被引：122

作者：

Ingale, Sachin A.

Seela, Frank ^{[1
]}

机构：

[1] Ctr Nanotechnol, Lab Bioorgan Chem & Chem Biol, D-48149 Munster, Germany

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 77卷 / 20期

关键词：

ZINC; SENSOR; CHEMISTRY; CD2+; OLIGONUCLEOTIDES; PROBE; IONS;

D O I：

10.1021/jo3014319

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new, easy-to-prepare and highly selective pyrene-linked tris-triazole amine fluorescent chemosensor has been designed from tripropargylamine and pyrene azide using Cu(I)-catalyzed click chemistry. The fluorescence on-off sensor 1 is highly selective for Zn2+ displaying a ratiometric change in emission. The relative intensity ratio of monomer to excimer fluorescence (M-376/E-465) of the sensor increases 80-fold upon the addition of 10 equiv of Zn2+ ions (with a detection limit of 0.2 mu M).

引用

收藏

页码：9352 / 9356

页数：5

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