Neo-clerodane diterpenoids from Teucrium polium

被引：31
|
作者：
Bedir, E
Tasdemir, D
Çalis, I [1 ]
Zerbe, O
Sticher, O
机构：
[1] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey
[2] Swiss Fed Inst Technol, Dept Pharm, CH-8057 Zurich, Switzerland
来源：
PHYTOCHEMISTRY | 1999年 / 51卷 / 07期
关键词：
Teucrium polium; Lamiaceae; diterpenoids; neo-clerodane derivative; teulolins A; B;
D O I：
10.1016/S0031-9422(99)00052-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two new neo-clerodane type diterpenoids, teulolin A (15,16-epoxy-6 beta,7 beta,18,19-tetrahydroxy-neo-cleroda-3(4),13(16),14-trien-20,12(S)-olide, 1) and teulolin B (15,16-epoxy-3 alpha, 6 beta, 7 beta, 18, 19-tetrahydroxy-neo-cleroda-4(18),13(16),14-trien-20,12(S)-olide, 2) were isolated from the aerial parts of Teucrium polium. The structures of 1-2 were proposed on the basis of extensive NMR experiments and molecular modeling studies. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：921 / 925
页数：5
相关论文
共 50 条
  • [41] TEUPONXN: A NEO-CLERODANE DITERPENE FROM TEUCRIUM JAPONICUM
    Zhi Da MIN~1~*
    ChineseChemicalLetters, 1991, (05) : 371 - 372
  • [42] TEUSCORODIN, TEUSCORODONIN AND 2-HYDROXYTEUSCOROLIDE, NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-SCORODONIA
    MARCO, JL
    RODRIGUEZ, B
    PASCUAL, C
    SAVONA, G
    PIOZZI, F
    PHYTOCHEMISTRY, 1983, 22 (03) : 727 - 731
  • [43] TEUGIN, A NEO-CLERODANE DITERPENOID FROM TEUCRIUM FRAGILE
    BRUNO, M
    SAVONA, G
    PASCUAL, C
    RODRIGUEZ, B
    PHYTOCHEMISTRY, 1981, 20 (09) : 2259 - 2261
  • [44] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-CHAMAEDRYS - THE IDENTITY OF TEUCRIN-B WITH DIHYDROTEUGIN
    RODRIGUEZ, MC
    BARLUENGA, J
    PASCUAL, C
    RODRIGUEZ, B
    SAVONA, G
    PIOZZI, F
    PHYTOCHEMISTRY, 1984, 23 (12) : 2960 - 2961
  • [45] Cytotoxic activity of neo-clerodane diterpenoids
    Gordaliza, M
    delCorral, JMM
    delaPuente, ML
    GarciaGravalos, MD
    SanFeliciano, A
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1997, 7 (13) : 1649 - 1654
  • [46] NEO-CLERODANE DITERPENOIDS FROM AJUGA-PSEUDOIVA
    CAMPS, F
    COLL, J
    DARGALLO, O
    PHYTOCHEMISTRY, 1984, 23 (02) : 387 - 389
  • [47] NEO-CLERODANE DITERPENOIDS FROM AJUGA-CHAMAEPITYS
    CAMPS, F
    COLL, J
    DARGALLO, O
    PHYTOCHEMISTRY, 1984, 23 (11) : 2577 - 2579
  • [48] Neo-clerodane diterpenoids from Ajuga pseudoiva leaves
    Ben Jannet, H
    Chaari, A
    Mighri, Z
    Martin, MT
    Loukaci, A
    PHYTOCHEMISTRY, 1999, 52 (08) : 1541 - 1545
  • [49] DIHYDROTEUGIN, A NEO-CLERODANE DITERPENOID FROM TEUCRIUM-CHAMAEDRYS
    SAVONA, G
    GARCIAALVAREZ, MC
    RODRIGUEZ, B
    PHYTOCHEMISTRY, 1982, 21 (03) : 721 - 723
  • [50] TEUMARIN, A NEO-CLERODANE DITERPENOID FROM TEUCRIUM-MARUM
    SAVONA, G
    PIOZZI, F
    SERVETTAZ, O
    FERNANDEZGADEA, F
    RODRIGUEZ, B
    PHYTOCHEMISTRY, 1984, 23 (03) : 611 - 613
12345